|
S1141
|
17-AAG (Tanespimycin) |
17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50of 5 nM. |
|
|
|
S1069
|
AUY922 (NVP-AUY922) |
NVP-AUY922 (VER-52296) is a highly potent HSP90 inhibitor for HSP90α and HSP90β with IC50 of 13 nM and 21 nM, respectively. |
|
|
|
S1052
|
Elesclomol |
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells.. |
|
|
|
S1159
|
Ganetespib (STA-9090) |
Ganetespib is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells. |
|
|
|
S1142
|
17-DMAG HCl (Alvespimycin) |
17-DMAG (Alvespimycin, KOS-1022, NSC 707545) is a potent HSP90 inhibitor with IC50 of 62 nM. |
|
|
|
S2713
|
Geldanamycin |
Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM. |
|
|
|
S1163
|
AT13387 |
AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells. |
|
|
|
S1498
|
NVP-BEP800 |
NVP-BEP800 is a novel, fully synthetic HSP90β inhibitor with IC50 of 58 nM. |
|
|
|
S1175
|
BIIB021 |
BIIB021 is a novel inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectivley. |
|
|
|
S2639
|
SNX-2112 |
SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, respectively. |
|
|
