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S7867
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Oleuropein
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Oleuropein is an antioxidant polyphenol isolated from olive leaf. It exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. This compound inhibits PPARγ activity. It exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. This chemical also inhibits aromatase. It induces apoptosis. Phase 2.
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S7594
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Abscisic Acid (Dormin)
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Abscisic Acid (Dormin, Abscisin II) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.
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S7582
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Anacardic Acid
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Anacardic Acid (6-pentadecylsalicylic Acid) is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity,
prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.
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S8036
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Butein
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Butein, a plant polyphenol isolated from Rhus verniciflua, is able to inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also inhibits EGFR.
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S7025
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Embelin
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Embelin (Embelic Acid, NSC 91874), a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.
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S4033
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Sennoside A
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Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
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S4018
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Sennoside B
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Sennoside B, a kind of irritant laxative isolated from rhei rhizome, inhibits PDGF-stimulated cell proliferation.
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S2252
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(+)-Usniacin
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(+)-Usniacin (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.
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S2253
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3-Indolebutyric acid (IBA)
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3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.
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S2424
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Hypoxanthine
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Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.
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S2374
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5-hydroxytryptophan (5-HTP)
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5-Hydroxytryptophan (5-HTP, NSC-92523), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression.
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S2256
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4-Methylumbelliferone (4-MU)
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4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.
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S2375
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Aloin (Barbaloin)
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Aloin (Barbaloin), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
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S2258
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Esculin
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Esculin (Aesculin) is a glucoside found in horse chestnuts.
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S2377
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Biochanin A
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Biochanin A (4-Methylgenistein), an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.
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S2259
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Aloe-emodin
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Aloe-emodin (NSC 38628, Rhabarberone) is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.
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S3071
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Vanillin
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Vanillin is a single molecule extracted from vanilla beans and is also a odor widely used in perfumes, foods and active molecules.
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S2260
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Amygdalin
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Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.
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S2379
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Dioscin
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Dioscin (Collettiside III, Saponin) is a saponin extracted and isolated from Polygonatum Zanlanscianense Pamp, showing antitumor activities.
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S2261
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Andrographolide
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Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.
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