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S3922
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(-)-epigallocatechin
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(-)-Epigallocatechin, widespread in plants, has been shown to exhibit anti-tumor, anti-cancer and anti-inflammatory functions.
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S3923
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Ginsenoside Rg1
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Ginsenoside Rg1 (Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1), one of the major active components of ginseng, is identified as a protopanaxatriol-type and has pharmacological actions such as neuroprotective and anti-tumor effects on various cancer types. This compound reduces cerebral Aβ levels and NF-κB nuclear translocation.
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S3924
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Ginsenoside Rb1
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Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. This compound, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. It also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. This chemical reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.
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S3925
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(-)-Epicatechin gallate
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(-)-Epicatechin gallate (ECG) is an inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 7.5 μM.
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S3926
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Forsythin
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Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.
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S2317
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L-(+)-Rhamnose Monohydrate
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L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.
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S3901
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Astragaloside IV
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Astragaloside IV (AST-IV, AS-IV) is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. AS-IV suppresses activation of p-Akt, p-mTOR, p-NF-κB and p-Erk1/2.
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S3915
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Gracillin
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Gracillin, a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica, has been reported to exert antitumor activity.
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S3916
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Macranthoidin B
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Macranthoidin B (Macranthoiside I) is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae.
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S3920
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7β-Hydroxylathyrol
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7β-Hydroxylathyrol (7beta-Hydroxylathyrol, 7-Hydroxylathyrol) is natural occuring product extracted from the seeds of Euphorbia lathyris L.
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S3921
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Lathyrol
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Lathyrol is a natural product that is used for cancer treatment.
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S3931
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Ginsenoside Rd
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Ginsenoside Rd (Panaxoside Rd, Sanchinoside Rd), a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. This compound inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. It inhibits expression of COX-2 and iNOS mRNA. This chemical also inhibits Ca2+ influx. It inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.
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S3765
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Picroside II
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Picroside II (6-Vanilloylcatalpol, Vanilloyl catalpol) is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
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S3875
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Alpinetin
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Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number of biological properties, such as antibacterial, antitumor and other important therapeutic activities. This compound is a flavonoid isolated from Alpinia katsumadai Hayata, activates PPAR-γ, with potent anti-inflammatory activity.
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S3878
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Bavachinin
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Bavachinin (7-O-Methylbavachin) is a novel natural pan-PPAR agonist from the fruit of the traditional Chinese glucose-lowering herb malaytea scurfpea. It shows stronger activities with PPAR-γ than with PPAR-α and PPAR-β/δ (EC50 = 0.74 μmol/l, 4.00 μmol/l and 8.07 μmol/l in 293T cells, respectively).
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S3881
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Scopoletin
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Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.
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S3883
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Protopine
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Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.
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S3884
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Jatrorrhizine
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Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
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S3800
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Lycorine hydrochloride
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Lycorine (Galanthidine, Amarylline, Narcissine, Licorine), a natural alkaloid extracted from the Amaryllidaceae plant family, has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. It is an HCV inhibitor with strong activity.
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S3801
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Sodium Lauryl Sulfoacetate
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Sodium Lauryl Sulfoacetate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
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