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Natural Product Library
Cat.No. Product Name Information
S2380 Diosmetin Diosmetin (Luteolin 4-methyl ether) is a bioflavonoid found in spearmint, oregano, and many other plants.
S2262 Apigenin Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM.
S2263 Arbutin Arbutin (Uva, p-Arbutin, β-Arbutin) is a tyrosinase inhibitor with IC50 of 0.9 mM and 0.7 mM for Monophenolase and Diphenolase, respectively.
S2382 Evodiamine Evodiamine (Isoevodiamine), an alkaloid extract from the fruit of Evodiae Fructus exhibits antitumor activities against the human tumor cells. It is shown to inhibit NF-κB activation through suppression of IkB kinase activity.
S2384 Hematoxylin Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.
S2266 Asiatic Acid Asiatic acid (Dammarolic acid, Asiantic acid) is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.
S2386 Indirubin (NSC 105327) Indirubin (NSC 105327) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM.
S2267 Azomycin Azomycin (2-Nitroimidazole) is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.
S2268 Baicalein Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.
S2269 Baicalin Baicalin is an inhibitor of prolyl oligopeptidase and also is an allosteric activator of carnitine palmityl transferase 1 (CPT1). This compound reduces the expression of NF-κB.
S2389 Naringin Dihydrochalcone Naringin Dihydrochalcone(Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin and also an inhibitor of CYP enzymes.
S1643 Ursodiol Ursodiol (Ursodeoxycholic acid, UDCA) reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones. (IC50=0.22 μM)
S2270 Bergenin Bergenin (Cuscutin) is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.
S2390 (E/Z)-Polydatin (E/Z)-Polydatin is a mixture of cis- and trans-configurations of Polydatin.
S2271 Berberine chloride Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids. This compound activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. It decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. This chemical induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. It is a dual topoisomerase I and II inhibitor. It is also a potential autophagy modulator.
S2391 Quercetin (Sophoretin) Quercetin, a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Quercetin induces mitophagy, apoptosis and protective autophagy. Phase 4.
S3600 Schisandrin B Schisandrin B is the most abundant dibenzocyclooctadiene lignan present in the traditional Chinese medicinal herb Schisandra chinensis (Turcz.) Baill. It is a kind of ATR and P-gp inhibitor with high safety.
S2273 β-Sitosterol β-Sitosterol (SKF 14463, 22,23-Dihydrostigmasterol) is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol.
S2392 Sesamin Sesamin (Fagarol, Fsesamin), a lignan isolated from the bark of Fagara plants and from sesame oil, exhibits various health benefits.
S2448 Gambogic Acid Gambogic Acid (Guttatic Acid, Guttic Acid, Beta-Guttiferrin) activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.