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S2276
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Bilobalide
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Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba.
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S2277
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Caffeic Acid
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Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO).
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S2281
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Chrysin
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Chrysin (NSC 407436) is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea).
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S2282
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Cinchonidine
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Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.
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S2422
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Ipriflavone (Osteofix)
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Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.
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S2285
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Cryptotanshinone (Tanshinone C)
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Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibiting phosphorylation of STAT3 Tyr705 with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. It also induces ROS-dependent autophagy and mitochondria-mediated apoptosis.
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S2423
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(S)-10-Hydroxycamptothecin
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(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor with potent anti-tumor activity.
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S2437
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Rotundine
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Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
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S2287
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Cytisine
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Cytisine (Baphitoxine, Sophorine) is a nicotinic acetylcholine receptor agonist.
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S2289
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Daidzin
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Daidzin (Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside), a natural organic compound in the class of phytochemicals known as isoflavones, is a potent and selective inhibitor of human mitochondrial aldehyde dehydrogenase and inhibits ALDH-I selectively (Ki=20 nM); at least 500 times less effective against ALDH-Ⅱ, the cytosolic isozyme (Ki=10 μM).
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S2385
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Hordenine
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Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
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S2394
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Naringenin
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Naringenin (NSC 34875, S-Dihydrogenistein, NSC 11855, Salipurol) is a natural predominant flavanone derived from plant food, which is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator.
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S2292
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Diosmin
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Diosmin is an agonist of the aryl hydrocarbon receptor (AhR). This compound is a semisynthetic phlebotropic agent and a flavonoid found in a variety of citrus fruits.
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S1973
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Cyclocytidine HCl
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Cyclocytidine (NSC 145668) is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia.
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S2296
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Enoxolone
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Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.
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S2395
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Rheochrysidin
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Rheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill.
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S2297
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Ergosterol
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Ergosterol is a sterol and a biological precursor (a provitamin) to vitamin D2.
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S2396
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Salidroside
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Salidroside (Rhodioloside), a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. This compound is a prolyl endopeptidase inhibitor. It alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. This chemical protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
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S2298
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Fisetin
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Fisetin (Fustel) is a potent sirtuin activating compound (STAC) and an agent that modulates sirtuins.
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S2397
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Palmatine chloride
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Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.
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