Catalog No.S1644

Nitrofural is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)

Price Stock Quantity  
In DMSO USD 190 In stock
USD 97 In stock
USD 207 In stock
Bulk Inquiry

Massive Discount Available

Free Overnight Delivery on all orders over $ 500.

Nitrofural Chemical Structure

Nitrofural Chemical Structure
Molecular Weight: 198.14

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Nitrofural is available in the following compound libraries:

Product Information

Product Description

Biological Activity

Nitrofurazone is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 µM, and effective against gram-negative and gram-positive bacteria. (Rat LD50 = 590 mg/kg)[1] Nitrofurazone (NF) and its derivative, hydroxymethylnitrofurazone (NFOH), have presented antichagasic activity. In vitro cruzain inhibition tests were performed for both compounds, and the 50% inhibitory concentration (IC50) for NF and NFOH presented values of 22.83 ± 1.2 µM and 10.55 ± 0.81 µM, respectively. AM1 semi-empirical molecular modeling studies were performed to understand the activity of the compounds, corroborating the observed cruzain inhibitory activity. [2]

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDog
Weight (kg)
Body Surface Area (m2)0.0070.0250.
Km factor36128520
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)

Chemical Information

Download Nitrofural SDF
Molecular Weight (MW) 198.14


CAS No. 59-87-0
Storage 3 years -20℃powder
6 months-80℃in solvent
Synonyms Nitrofurazone
Solubility (25°C) * In vitro DMSO 40 mg/mL (201.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name 2-​[(5-​nitro-​2-​furanyl)​methylene]​-hydrazinecarboxamide

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Related Others Products

Recently Viewed Items

Tags: buy Nitrofural | Nitrofural ic50 | Nitrofural price | Nitrofural cost | Nitrofural solubility dmso | Nitrofural purchase | Nitrofural manufacturer | Nitrofural research buy | Nitrofural order | Nitrofural mouse | Nitrofural chemical structure | Nitrofural mw | Nitrofural molecular weight | Nitrofural datasheet | Nitrofural supplier | Nitrofural in vitro | Nitrofural cell line | Nitrofural concentration | Nitrofural nmr
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description
Contact Us