Anti-infection

Cat.No. Product Name Information Product Use Citations Product Validations
S4592 SBE-β-CD SBE-β-CD is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.
Autophagy, 2025, 21(8):1824-1842
Int J Mol Sci, 2025, 26(2)490
Front Pharmacol, 2025, 16:1625798
S5001 CP-690550 (Tofacitinib) Citrate Tofacitinib citrate (CP-690550, Tasocitinib) is a novel JAK inhibitor with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. It also has anti-infection activity.
Cells, 2025, 14(2)102
Front Pharmacol, 2025, 16:1549183
J Exp Clin Cancer Res, 2024, 43(1):64
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S7465 FTI 277 HCl FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. This compound inhibits cell growth and induces apoptosis. This chemical is effective in clearing HDV viremia.
EMBO J, 2025, 44(4):1185-1219
BMC Biol, 2025, 23(1):233
PLoS One, 2025, 20(9):e0331440
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S4430 HCQ (Hydroxychloroquine) Sulfate Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
EMBO J, 2025, 10.1038/s44318-025-00581-3
iScience, 2025, 28(4):112054
Int J Mol Sci, 2025, 26(2)588
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S2271 Berberine chloride Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids. This compound activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. It decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. This chemical induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. It is a dual topoisomerase I and II inhibitor. It is also a potential autophagy modulator.
J Cardiovasc Dev Dis, 2025, 12(7)278
Adv Healthc Mater, 2023, e2300591.
Transl Oncol, 2023, 35:101712
S2613 Clorsulon Clorsulon (MK-401,L631529) is used in the treatment of Fasciola hepatica infections in calves and sheep.
iScience, 2024, 27(10):110862
J Pers Med, 2022, 12(2)258
Hum Cell, 2022, 10.1007/s13577-022-00671-y
S4147 Azithromycin Dihydrate Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.
J Cell Biochem, 2022, 10.1002/jcb.30213
Adv Ther (Weinh), 2020, 2000034
PLoS Comput Biol, 2020, 16(12):e1008489
S7896 Sodium Tauroursodeoxycholate (TUDC) Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.
iScience, 2024, 27(8):110598
Infect Immun, 2024, 92(8):e0030024
Microbiome, 2019, 7(1):145
S4237 Primaquine Diphosphate Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.
J Extracell Vesicles, 2024, 13(7):e12494
bioRxiv, 2024, 2024.10.28.620521
Front Pharmacol, 2021, 12:695009
S4420 Mefloquine HCl Mefloquine HCl(Mefloquin hydrochloride) is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.
Mol Med Rep, 2021, 23(1)40
bioRxiv, 2020, 2020/9/20.4.7.30734
Int J Parasitol Drugs Drug Resist, 2018, 8(2):331-340
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