Cetylpyridinium Chloride

Synonyms: CPC

Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.

Cetylpyridinium Chloride Chemical Structure

Cetylpyridinium Chloride Chemical Structure

CAS: 123-03-5

Selleck's Cetylpyridinium Chloride has been cited by 1 publication

Purity & Quality Control

Batch: S417201 DMSO] 68 mg/mL] false] Water] 68 mg/mL] false] Ethanol] 68 mg/mL] false Purity: 99.79%
99.79

Cetylpyridinium Chloride Related Products

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Biological Activity

Description Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
In vitro
In vitro

Cetylpyridinium chloride (CPC) as active ingredient of antiseptic oral mouthrinses has a broad antimicrobial spectrum with a rapid bactericidal effect on gram-positive pathogens and a fungicide effect on yeasts in particular. Application of CPC at a concentration of 0.05% as a mouthrinse results in an immediate reduction in bacterial counts of 2.0 to 2.5 log steps (which is adequate to > 99%). This reverts to about 1 log step (= 90%) 1 h after application. The ability of CPC to inhibit plaque and thereby reduce gingivitis is assured. In comparison to chlorhexidine, CPC has a lower residual effect, and as a result a lesser effect against plaque and gingivitis. The efficacy of CPC against oropharyngeal candidiasis is assured. CPC mouthrinses can significantly reduce infectious aerosols in dental practice, thereby protecting both staff and the patient. The balance of intra-oral bacterial flora is not disturbed even in the case of relatively long-term use of CPC (up to six weeks). [1]

In Vivo
In vivo

Cetylpyridinium chloride increases the risk of severe allergic reactions, such as swelling of the mouth, face, lips or tongue, labored breathing, rashes, and hives. Ingesting high concentrations of cetylpyridinium chloride can lead to lung damage. Cetylpyridinium chloride is toxic if swallowed or inhaled. [2]

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Chemical Information & Solubility

Molecular Weight 339.99 Formula

C21H38N.Cl

CAS No. 123-03-5 SDF Download Cetylpyridinium Chloride SDF
Smiles CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1.[Cl-]
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 68 mg/mL ( (200.0 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 68 mg/mL

Ethanol : 68 mg/mL


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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