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Human epidermal growth factor receptor 2
| Cat.No. | Product Name | Feedback | Added |
|---|---|---|---|
| S1486 | AEE788 | Sep 2010 | |
| AEE788 is a novel multitargeted human epidermal receptor (HER) 1/2 and vascular endothelial growth factor receptor (VEGFR) 1/2 receptor family tyrosine kinases inhibitor with IC50 of 2, 6, 77, 59 nM for EGFR, ErbB2, KDR, and Flt-1. | |||
| S1011 | BIBW2992 (Afatinib) |  | Apr 2009 |
| BIBW2992 (Afatinib) is an irreversible EGFR/HER2 inhibitor with an IC50 of 0.5, 0.4, 10, 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 in vitro, respectively. | |||
| S1019 | CI-1033 (Canertinib) | | Apr 2009 |
| CI-1033 (Canertinib) is an orally bioavailable irreversible Pan-erbB tyrosine kinase inhibitor, targeting EGFR with IC50 of 0.8, 19 and 7 nM for EGFR, HER-2 and ErbB-4, respectively. | |||
| S1167 | CP-724714 | Mar 2010 | |
| CP-724714 is a HER-2 tyrosine kinase inhibitor, IC50 of 15 ng/ml | |||
| S1028 | Lapatinib (Tykerb) | | Apr 2009 |
| EGFR and HER2 autophosphorylation inhibitor, against purified EGFR and HER2 of 10.2 and 9.8 nM, respectively. | |||
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Customer's Feedback
| Dongfeng Chen, The Rausing Lab |
| "Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future." |
| R.B. Cambridge |
| "I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more." |
| Zhenghe John Wang Assistant Professor, Case Western Reserve University |
| "We have purchased LBH-589, Saha and MS-275 from you and they all worked well." |
| Jenny Sun |
| "We used the LBH-589 in our experiments. The compound is easy to use with excellent reproducibility." |
| Yu Wang, Harvard University |
| "The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research." |
| Dung-Fang Lee |
| "Based on our preliminary data, I found MLN8237 and VX-680 have good effects in inhibiting Aurka-maintaining ESC self-renewal in mouse ES cells." |
Latest Catalog
| May 2010 Selleck Latest Catalog |  |
