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(-)-Epigallocatechin gallate

Catalog No.S2250
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$ 70
 
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(-)-Epigallocatechin gallate Chemical Structure

  • [Ala92]-p16 (84-103)

    [Ala92]-p16 (84-103) is a CDK inhibitor with IC50 of 1.5μM for cyclin-dependent kinase-4 (cdk4)/cyclin D1

  • Bax inhibitor peptide,negative control

    Bax inhibitor peptide,negative control is a negative control peptide for the Bax inhibitor peptides V5 and P5.

  • JIP-1(153-163)

    JNK and p38 MAPK inhibitor

  • STF-62247

    Targeting VHL-deficient RCC cells, in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 μM).

  • BTZ043 racemate

    BTZ043 racemate is a decaprenylphosphoryl-b-D-ribose 2’-epimerase inhibitor with MIC of 2.3 and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.

  • GSK690693

    GSK690693 is a pan-Akt kinase inhibitor,IC50 of Akt 1, 2, and 3 at 2, 13, and 9 nM respectively.

  • Odanacatib (MK 0822)

    cathepsin K inhibitor with an IC50 of 0.2nM.

  • Malotilate

    Malotilate is a liver protein metabolism improved compound.

  • PA-824

    PA-824 is an experimental anti-tuberculosis drug with MIC of less than 1 μg/mL for tuberculosis.

Biological Activity

(-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea. It is the ester of epigallocatechin and gallic acid, and is a type of catechin. Its possible benefit as a nutritional chemopreventive agent for cancer, atherosclerosis, and neurodegenerative diseases is generating increased scientific interest. EGCG has demonstrated chemopreventive and chemotherapeutic actions in cellular and animal models of cancer. [1][2]

Molecular Weight (WM): 458.37
Formula:

C22H18O11

CAS No.: 989-51-5
Synonyms:
EGCG
Dissolve in (25°C): DMSO ≥92mg/mL 
Water ≥23mg/mL 
Ethanol ≥92mg/mL 
Storage: 2 years-20°CPowder
1 week-4°Cin DMSO
1 month-80°in DMSO

Research Area

Related Inhibitors

Recommended Screening Libraries

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