- Inhibitory Selectivity
|Catalog No.||Product Name||Solubility(25°C)|
|S1466||Calcitriol||<1 mg/mL||83 mg/mL||83 mg/mL|
|S1468||Alfacalcidol||<1 mg/mL||80 mg/mL||80 mg/mL|
|S3114||Vitamin C||35 mg/mL||35 mg/mL||<1 mg/mL|
|S1467||Doxercalciferol||<1 mg/mL||83 mg/mL||70 mg/mL|
|S1469||Calcifediol||<1 mg/mL||80 mg/mL||20 mg/mL|
|S3665||Trolox||<1 mg/mL||50 mg/mL||50 mg/mL|
|S3130||Biotin (Vitamin B7)||<1 mg/mL||49 mg/mL||<1 mg/mL|
|S1902||Vitamin B12||6 mg/mL||75 mg/mL||10 mg/mL|
|S1921||Phenindione||<1 mg/mL||44 mg/mL||15 mg/mL|
|S1744||Nicotinic Acid||2 mg/mL||25 mg/mL||<1 mg/mL|
|S4063||Vitamin D3||<1 mg/mL||77 mg/mL||77 mg/mL|
|S1767||Beta Carotene||<1 mg/mL||4 mg/mL||5 mg/mL|
|S2540||Riboflavin||<1 mg/mL||0.1 mg/mL||<1 mg/mL|
|S3211||Thiamine HCl (Vitamin B1)||68 mg/mL||<1 mg/mL||<1 mg/mL|
|S4503||Calcium D-Panthotenate||44 mg/mL||44 mg/mL||<1 mg/mL|
|S4126||Retinyl (Vitamin A) Palmitate||<1 mg/mL||3 mg/mL||5 mg/mL|
|S4144||Amprolium HCl||63 mg/mL||2 mg/mL||<1 mg/mL|
|S4605||Folic acid||<1 mg/mL||2 mg/mL||<1 mg/mL|
|S2297||Ergosterol||<1 mg/mL||0.01 mg/mL||<1 mg/mL|
|S4083||Vitamin A Acetate||<1 mg/mL||65 mg/mL||65 mg/mL|
|S3113||Pyridoxine HCl||41 mg/mL||41 mg/mL||<1 mg/mL|
|S4245||Sodium ascorbate||40 mg/mL||2 mg/mL||<1 mg/mL|
- Vitamin Inhibitors (23)
- New Vitamin Products
|Catalog No.||Information||Product Use Citations||Product Validations|
Calcitriol is a nonselective vitamin D receptor activator/agonist(VDRA), exhibiting a 10-fold higher vitamin D receptor (VDR) binding affinity(IC50=0.4 nM) than the selective VDRA paricalcitol.
Alfacalcidol is a non-selective VDR activator medication.
Vitamin D analogs induce adenylate kinase release from S. mutans planktonic cells. S. mutans UA159 cultures were grown in TY medium + 1% (w/v) glucose to exponential phase and used to inoculate fresh medium containing ciprofloxacin (positive control), DMSO (negative control), alfacalcidol, calcitriol, or doxercalciferol at 16, 32, and 64 μg/mL for 4h. Cell lysis was detected using the AK assay as described in Materials and Methods. Data is represented as relative luminescence units (RLU) normalized to background (DMSO) and is representative of three replicate cultures performed in triplicate. (* p<0.05; Student’s t-Test; two-tailed).
Vitamin C is a water-soluble vitamin indicated for the prevention and treatment of scurvy.
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM).
(E) Qualitative representations of zebrafish larvae, showing ISV to be unchanged or slightly reduced in response to 20 μM seocalcitol, maxacalcitol, calcitriol, calcifediol and tacalcitol treatment between 6 hpf and 2 dpf. Scale bar represents 200 μm. (F) Qualitative representation of intact ISV after 10 μM seocalcitol, maxacalcitol, calcitriol, calcifediol and tacalcitol treatment from 2-5 dpf. Scale bar represents 200 μm.
Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.
Biotin is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.
Vitamin D3 is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM.
Beta Carotene is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A.
Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.
Calcium D-Panthotenate, also called vitamin B5 Calcium, is a water-soluble vitamin and an essential nutrient for many animals.
Vitamin A palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid.
Amprolium chloride is a thiamin antagonist, which prevents carbohydrate synthesis by blocking thiamine uptake.
Folic acid, a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.
Ergosterol is a sterol and a biological precursor (a provitamin) to vitamin D2.
Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
Vitamin A is a group of unsaturated nutritional hydrocarbons, that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids, among which beta-carotene is the most important.
Pyridoxine HCl is a form of vitamin B6.
Sodium Ascorbate is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.