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Vitamin B12

Name: Vitamin B12
Brand: Selleck Chemicals
SKU: S1902
Rating: 5 (3 reviews)

Synonyms: Cobalamin, Cyanocobalamin

Catalog No.S1902 Purity: 100.0%

Vitamin B12 (Cobalamin, Cyanocobalamin) is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

Vitamin B12 Chemical Structure

CAS: 68-19-9

Selleck's Vitamin B12 has been cited by 3 publications

Purity & Quality Control

Batch: Purity: 100.0%

100.0

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Choose Selective Vitamin Inhibitors

Biological Activity

Description	Vitamin B12 (Cobalamin, Cyanocobalamin) is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT04310059	Not yet recruiting	Thalassemia\|Folic Acid Deficiency Anemia	The University of Hong Kong\|Queen Mary Hospital Hong Kong	July 1 2024	Not Applicable
NCT06046703	Not yet recruiting	Vitamin B 12 Deficiency\|Pregnancy\|Nutrient Deficiency\|Dietary Exposure	Maastricht University Medical Center	January 1 2024	--
NCT06190314	Recruiting	Cerebrovascular Event\|Vitamin b12\|Hemorrhagic Stroke\|Ischemic Stroke	Hospital General de Mexicali\|Sandoval Briones Jocelin Lisset\|Hirata Medina Nancy Midory\|Felix Escobedo Marisol\|Cervantes De Carlos Cereza Guadalpe\|Aceves Lozano Natalia\|Cota Andara Manuel Eduardo\|Avila Pacheco Manlio Abraham\|Rodriguez Gonzalez Alondra\|Barruquin Sandoval Claudia Pamela\|González Gómez René Ignacio\|Jaramillo Ramirez Hiram Javier.	November 13 2023	--
NCT06085677	Not yet recruiting	Stomach Neoplasm\|Chronic Atrophic Gastritis\|Intestinal Metaplasia	Imperial College London\|University College London\|University of Oxford\|University of Copenhagen	November 4 2023	--
NCT06057597	Recruiting	Obesity\|Morbid	Assistance Publique - Hôpitaux de Paris	November 13 2023	Not Applicable

Chemical Information & Solubility

Molecular Weight	1355.37	Formula	C₆₃H₈₈CoN₁₄O₁₄P
CAS No.	68-19-9	SDF	Download Vitamin B12 SDF
Smiles	CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3]
Storage (From the date of receipt)	Store at 4℃(in the dark)	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	Store at 4℃(in the dark)		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (73.78 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 100 mg/mL

Water : 15 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

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