Naproxen

For research use only.

Catalog No.S5177

1 publication

Naproxen Chemical Structure

Molecular Weight(MW): 230.26

Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.

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Selleck's Naproxen has been cited by 1 publication

Purity & Quality Control

Choose Selective COX Inhibitors

Biological Activity

Description Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.

Protocol

References

Solubility (25°C)

In vitro DMSO 46 mg/mL (199.77 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 230.26
Formula

C14H14O3

CAS No. 22204-53-1
Storage powder
in solvent
Synonyms N/A
Smiles COC1=CC2=CC=C(C=C2C=C1)C(C)C(O)=O

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04145518 Recruiting Drug: Naproxen Sodium Dysmenorrhea (Disorder)|Dysmenorrhea Primary|Dysmenorrhea Secondary|Endometrial Diseases|Leiomyoma|Fibroid Uterus NorthShore University HealthSystem|National Institutes of Health (NIH)|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) October 25 2019 Phase 4
NCT03092193 Unknown status Drug: Naproxen|Drug: Naproxen-esomeprazole Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant|Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant University of Sao Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo March 1 2017 Phase 4
NCT02502006 Active not recruiting Drug: Celecoxib|Drug: Naproxen|Drug: Placebo Healthy University of Pennsylvania|National Heart Lung and Blood Institute (NHLBI) November 2015 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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COX Signaling Pathway Map

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