Molecular Weight(MW): 308.31
Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.
1 Customer Review
Nimesulide has no effect on KSHV lytic replication in BCBL-1 cells. The cells induced with TPA for 3 h were treated with the test compounds for 72 h. Then, the effect of nimesulide on cell viability (C) and the number of DNA copies (D) were measured as described in the Methods. CDV (20 µM) is a positive control for inhibiting viral DNA replication. Data were normalized as the fold change compared with the no-TPA induced control. The results are presented as the mean values with standard deviations (n = 3).
Viruses, 2015, 7(5):2268-87.. Nimesulide purchased from Selleck.
Purity & Quality Control
Choose Selective COX Inhibitors
|Description||Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.|
|In vitro||DMSO||62 mg/mL (201.09 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT01670552||Unknown status||Acute and Chronic Inflammation|Dyspepsia||EMS||February 2016||Phase 3|
|NCT03119324||Completed||Temporomandibular Joint Disorders||University of Roma La Sapienza||September 2015||Not Applicable|
|NCT01257126||Withdrawn||Upper Respiratory Tract Infections||Novartis Pharmaceuticals|Novartis||April 2011||Phase 4|
|NCT01745614||Completed||Pain||GlaxoSmithKline||July 18 2010||Phase 1|
|NCT01500577||Completed||Breast Cancer||European Institute of Oncology||April 2005||Phase 2|
|NCT02229747||Completed||Pharyngitis||Boehringer Ingelheim||August 2001||Phase 4|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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