For research use only.
CAS No. 51803-78-2
Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.
1 Customer Review
Nimesulide has no effect on KSHV lytic replication in BCBL-1 cells. The cells induced with TPA for 3 h were treated with the test compounds for 72 h. Then, the effect of nimesulide on cell viability (C) and the number of DNA copies (D) were measured as described in the Methods. CDV (20 µM) is a positive control for inhibiting viral DNA replication. Data were normalized as the fold change compared with the no-TPA induced control. The results are presented as the mean values with standard deviations (n = 3).
Viruses, 2015, 7(5):2268-87.. Nimesulide purchased from Selleck.
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|Description||Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.|
|In vitro||DMSO||62 mg/mL (201.09 mM)|
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|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
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|% DMSO % % Tween 80 % ddH2O|
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Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT01745614||Completed||Drug: Nimesulide 100 mg tablets||Pain||GlaxoSmithKline||July 18 2010||Phase 1|
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