Metamizole sodium hydrate

For research use only.

Catalog No.S4435 Synonyms: Dipyrone sodium hydrate

Metamizole sodium hydrate Chemical Structure

CAS No. 5907-38-0

Metamizole (Dipyrone) sodium hydrate is a potent inhitior of cyclooxygenase (COX) with strong analgesic as well as antipyretic and spasmolytic properties.

Purity & Quality Control

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Biological Activity

Description Metamizole (Dipyrone) sodium hydrate is a potent inhitior of cyclooxygenase (COX) with strong analgesic as well as antipyretic and spasmolytic properties.
Targets
COX [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 70 mg/mL (199.23 mM)
Water 70 mg/mL (199.23 mM)
Ethanol ''35 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 351.35
Formula

C13H18N3NaO5S

CAS No. 5907-38-0
Storage powder
in solvent
Synonyms Dipyrone sodium hydrate

In vivo Formulation Calculator (Clear solution)

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02660177 Completed Drug: Metamizole Children|Pain|Surgery University Children''s Hospital Basel April 2016 Phase 2
NCT02148939 Completed -- Ischemic Stroke Heinrich-Heine University Duesseldorf May 2014 --
NCT02712268 Completed Other: Checklist Elderly Internal Medicine Patients University Hospital Basel Switzerland September 2013 Not Applicable
NCT00410332 Unknown status Drug: Traumeel S|Drug: Placebo Post-Tonsillectomy Shaare Zedek Medical Center March 2011 Phase 3
NCT00799149 Completed Drug: Gabapentin Etoricoxib Sugar pill Knee Arthroscopy Meir Medical Center June 2006 Phase 4
NCT00635037 Completed Drug: bupivacaine and acupuncture Myofascial Pain Syndromes Federal University of São Paulo June 2004 Not Applicable

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COX Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID