CVT-10216

Catalog No.E0355

For research use only.

CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 with an IC50 of 29 nM.

CVT-10216 Chemical Structure

CAS No. 1005334-57-5

Purity & Quality Control

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Biological Activity

Description CVT-10216 is a highly selective, reversible inhibitor of ALDH-2 with an IC50 of 29 nM.
Targets
ALDH-2 [1]
()
ALDH-1 [1]
()
29 nM 1.3 μM

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 93 mg/mL
(199.79 mM)
Water Insoluble
Ethanol Insoluble

Chemical Information

Molecular Weight 465.48
Formula

C24H19NO7S

CAS No. 1005334-57-5
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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