Carbohydrate Metabolism

Inhibitory Selectivity

Carbohydrate Metabolism Products

Catalog No. Information Product Use Citations Product Validations
S2589

Miglitol

Miglitol is an oral anti-diabetic drug.

S3918

4',7-Dimethoxy-5-Hydroxyflavone

4',7-Dimethoxy-5-Hydroxyflavone (apigenin dimethylether) inhibits α-glucosidase and α-amylase enzymes and enhances 2-NBDG uptake in L6 cells.

S9378

4',5-Dihydroxyflavone

4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase.

S3796

Rebaudioside A

Rebaudioside A (Stevia Extract), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels.

S4101

Voglibose

Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.

S4793

Cedryl acetate

Cedryl Acetate, an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.

S5426

Bromopyruvic acid

Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.

S2610

Lonidamine

Lonidamine is an orally administered small molecule hexokinase inactivator.

S2155

LY2608204

LY2608204 activates glucokinase (GK) with EC50 of 42 nM. Phase 2.

S2035

Epalrestat

Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.

S3839

1-Deoxynojirimycin

1-Deoxynojirimycin is a potent α-glucosidase inhibitor and most commonly found in mulberry leaves. It has therapeutic potency against diabetes mellitus.

S4701

2-Deoxy-D-glucose

2-Deoxy-D-glucose, an analog of glucose, is a glycolytic inhibitor with antiviral activity. 2-Deoxy-D-glucose induces apoptosis and inhibits Herpes Simplex Virus type-1 (HSV-1) receptor expression.

S1950

Metformin HCl

Metformin HCl decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.

S1271

Acarbose

Acarbose is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.

Catalog No. Information Product Use Citations Product Validations
S2589

Miglitol

Miglitol is an oral anti-diabetic drug.

S3918

4',7-Dimethoxy-5-Hydroxyflavone

4',7-Dimethoxy-5-Hydroxyflavone (apigenin dimethylether) inhibits α-glucosidase and α-amylase enzymes and enhances 2-NBDG uptake in L6 cells.

S9378

4',5-Dihydroxyflavone

4',5-Dihydroxyflavone inhibits soybean LOX-1 and yeast α-glucosidase.

S3796

Rebaudioside A

Rebaudioside A (Stevia Extract), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels.

S4101

Voglibose

Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia.

S4793

Cedryl acetate

Cedryl Acetate, an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.

S5426

Bromopyruvic acid

Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.

Catalog No. Information Product Use Citations Product Validations
S2610

Lonidamine

Lonidamine is an orally administered small molecule hexokinase inactivator.

S2155

LY2608204

LY2608204 activates glucokinase (GK) with EC50 of 42 nM. Phase 2.

S2035

Epalrestat

Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.

S3839

1-Deoxynojirimycin

1-Deoxynojirimycin is a potent α-glucosidase inhibitor and most commonly found in mulberry leaves. It has therapeutic potency against diabetes mellitus.

S4701

2-Deoxy-D-glucose

2-Deoxy-D-glucose, an analog of glucose, is a glycolytic inhibitor with antiviral activity. 2-Deoxy-D-glucose induces apoptosis and inhibits Herpes Simplex Virus type-1 (HSV-1) receptor expression.

Catalog No. Information Product Use Citations Product Validations
S1950

Metformin HCl

Metformin HCl decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.

S1271

Acarbose

Acarbose is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.