Bismuth Subsalicylate

For research use only.

Catalog No.S4032

Bismuth Subsalicylate Chemical Structure

CAS No. 14882-18-9

Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.

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Biological Activity

Description Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.
Targets
prostaglandin G/H Synthase 1/2 [1]
In vitro

Bismuth Subsalicylate reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H Synthase 1/2. [1] Bismuth Subsalicylate is the active ingredient in Pepto-Bismol, an anti-diarrhea medication and antacid. In the gastrointestinal tract, Bismuth Subsalicylate is converted to salicylic acid and insoluble bismuth salts. [2]

Protocol

Solubility (25°C)

In vitro DMSO 0.04 mg/mL (0.11 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 362.09
Formula

C7H5BiO4

CAS No. 14882-18-9
Storage powder
in solvent
Synonyms N/A
Smiles C1=CC=C2C(=C1)C(=O)O[Bi]O2.O

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID