CAS No. 14882-18-9
| IUPAC Name | bismuth;2-oxidobenzoate;hydroxide | |
|---|---|---|
| CAS Number | 14882-18-9 | |
| Molecular Formula |
C7H5BiO4 |
|
| Molecular Weight (MW) | 362.09 | |
| SMILES | C1=CC=C2C(=C1)C(=O)O[Bi]O2.O | |
| InChIKey | ZREIPSZUJIFJNP-UHFFFAOYSA-K |
Bismuth subsalicylate is a gastrointestinal protective agent that acts as an inhibitor of prostaglandin G/H synthase 1 and 2 (COX-1/COX-2). By suppressing prostaglandin synthesis, the compound modulates mucosal inflammatory pathways and reduces hypersecretion in intestinal tissues. This action leads to attenuated pro-inflammatory signaling and diminished fluid secretion, contributing to its antisecretory and anti-inflammatory cellular effects in gastrointestinal epithelial models. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| 5%TFA | 3.04 mg/mL |
| DMSO |
0.04 mg/mL
(0.11 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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