Rutaecarpine

Catalog No.S2349 Synonyms: Rutecarpine

For research use only.

Rutaecarpine (Rutecarpine) is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs; a new class of COX-2 inhibitor.

Rutaecarpine Chemical Structure

CAS No. 84-26-4

Selleck's Rutaecarpine has been cited by 1 Publication

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Biological Activity

Description Rutaecarpine (Rutecarpine) is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs; a new class of COX-2 inhibitor.
Targets
COX2 [3]
In vitro

Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs, which has shown a variety of intriguing biological properties such as anti-thrombotic, anticancer, anti-inflammatory and analgesic, anti-obesity and thermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular and endocrine systems. [1]

In vivo LD50: Mice 65mg/kg (i.v.). [2]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 287.32
Formula

C18H13N3O

CAS No. 84-26-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1CN2C(=NC3=CC=CC=C3C2=O)C4=C1C5=CC=CC=C5N4

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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