Molecular Weight(MW): 270.24
Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.
Cited by 7 Publications
5 Customer Reviews
Baicalein suppresses the viability of DU 145 and PC-3 cells. b DU145 cells and c PC-3 cells were treated with different concentrations of baicalein for 24, 48, and 72 h. Baicalein significantly inhibited the viability of both cell lines in a dose-and time-dependent manner. The results are presented as the means ± SD of three independent experiments and the corresponding standard error. *P<0.05; **P<0.01.
Mol Cell Biochem, 2015, 406:111–119.. Baicalein purchased from Selleck.
NKILA stably overexpressed and control SMMC-7721 and HepG2 cells were treated with a series dose of Baicalein (0, 12.5, 25, 50, 100 μM) for 48 h. Then, cell proliferation was detected by Glo cell viability assays. The control condition was defined as media alone with no NKILA overexpression.
Chem Biol Interact, 2018, 285:48-58. Baicalein purchased from Selleck.
Baicalein downregulated BDLNR in dose and time dependent fashion in cervical cancer cells. (A, B) After being treated with indicated dose of baicalein for 24 h, BDLNR expression in HeLa (A) or SiHa (B) cells was measured by qRT-PCR and normalized to β-actin. (C, D) After being treated with 100 μM baicalein for indicated time, BDLNR expression in HeLa (C) or SiHa (D) cells was measured by qRT-PCR and normalized to β-actin. Results are shown as mean ± SD (n = 3). **P < 0.01, *** P < 0.001 by Student’s t test.
Int J Biochem Cell Biol, 2018, 94:107-118. Baicalein purchased from Selleck.
Baicalein activated PAX8-AS1-N expression in dose and time dependent manners in breast cancer cells. A and B, After treatment with indicated doses of baicalein for 48 h, PAX8-AS1-N expression in MDA-MB-231 (A) or MCF-7 (B) cells was measured by qRT-PCR and normalized to β-actin. C and D, After treatment with 200 µM baicalein for indicated time, PAX8-AS1-N expression in MDA-MB-231 (C) or MCF-7 (D) cells was measured by qRT‐PCR and normalized to β-actin. Results are shown as mean ± SD from three independent experiments. **P < 0.01, **P < 0.001 by Student's t-test.
J Cell Biochem, 2018, 119(8):6842-6856. Baicalein purchased from Selleck.
Purity & Quality Control
Choose Selective P450 (e.g. CYP17) Inhibitors
|Description||Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.|
|In vitro||DMSO||54 mg/mL (199.82 mM)|
|In vivo||Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+45% PEG 300+ddH2O
For best results, use promptly after mixing.
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