Catalog No.S2329 Synonyms: Naringoside
Molecular Weight(MW): 580.53
Naringin is a flavanone glycoside, which exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes.
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|Description||Naringin is a flavanone glycoside, which exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes.|
Naringin is a flavanone glycoside, which gives the grapefruit juice its bitter taste. Naringin inhibits hepatic P-glycoprotein (P-gp) and some drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions.  Naringin is also an inhibitor of vascular endothelial growth factor (VEGF) release, which causes angiogenesis.  In addition, Naringin reduces diabetes-induced neuropathy in rats. 
|In vivo||LD50: Mice 1650mg/kg. |
|In vitro||DMSO||100 mg/mL (172.25 mM)|
|Ethanol||2 mg/mL (3.44 mM)|
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