Flubendazole

Catalog No.S1837

Flubendazole is an anthelmintic agent for MDAY-D2 cells with IC50 of 3 nM.

Price Stock Quantity  
USD 97 In stock
Bulk Inquiry

Massive Discount Available

Free Overnight Delivery on all orders over $ 500.

Flubendazole Chemical Structure

Flubendazole Chemical Structure
Molecular Weight: 313.28

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Flubendazole is available in the following compound libraries:

Product Information

  • Compare Others
    Compare Others Products

Product Description

Biological Activity

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesBaboonDogMonkeyRabbitGuinea pigRatHamsterMouse
Weight (kg)121031.80.40.150.080.02
Body Surface Area (m2)0.60.50.240.150.050.0250.020.007
Km factor202012128653
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)

Chemical Information

Download Flubendazole SDF
Molecular Weight (MW) 313.28
Formula

C16H12FN3O3

CAS No. 31430-15-6
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Synonyms
Solubility (25°C) * In vitro DMSO 1 mg/mL (3 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Related Others Products

  • AZ191

    AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively.

  • PTC-209

    PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).

  • (S)-crizotinib

    (S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM.

  • CX-4945 (Silmitasertib)

    CX-4945 (Silmitasertib) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Phase 1/2.

    Features:First clinical inhibitor of CK2.

  • Tacrolimus (FK506)

    FK-506 is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex.

  • Verteporfin

    Verteporfin is a potent second-generation photosensitizing agent derived from porphyrin.

  • Cyclosporin A

    Cyclosporin A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM, widely used in organ transplantation to prevent rejection.

  • Bendamustine HCl

    Bendamustine HCL is a DNA-damaging agent with IC50 of 50 μM.

  • Cyclophosphamide Monohydrate

    Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA.

  • Calcitriol

    Calcitriol is the hormonally active form of vitamin D.

Recently Viewed Items

Tags: buy Flubendazole | Flubendazole ic50 | Flubendazole price | Flubendazole cost | Flubendazole solubility dmso | Flubendazole purchase | Flubendazole manufacturer | Flubendazole research buy | Flubendazole order | Flubendazole mouse | Flubendazole chemical structure | Flubendazole mw | Flubendazole molecular weight | Flubendazole datasheet | Flubendazole supplier | Flubendazole in vitro | Flubendazole cell line | Flubendazole concentration | Flubendazole nmr
Contact Us