Proteasome

Cat.No. Product Name Feedback Added

S1457

Atazanavir(BMS-232632)

Jul 2010
Atazanavir (Reyataz, BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class.
S1013

Bortezomib (Velcade)

Apr 2009
Bortezomib (Velcade) also known as Velcade, MG-341, PS-341 is proteasome Inhibitor, effectively inhibits proteasome activity (Ki-0.6 nM).
S2619

MG-132

Jun 2011
MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50 of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.
S2180

MLN2238

Jan 2011
MLN2238 is a potent reversible and specific β5 site of the 20S proteasome inhibitor with an IC50 value of 3.4 nM.
S2181

MLN9708

Jan 2011
MLN9708 is an orally bioavailable second generation proteasome inhibitor with potential antineoplastic activity.
S1185

Ritonavir

Apr 2010
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.
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Customer's Feedback
Arnaud AUTRET, Trinity College
"I would like to confirm you that everything is perfectly fine with ABT and Obatoclax we got from your company. We confirmed their activity in vitro. We notably observed their impact in an apoptotic model and results are similar to those which have been published."

Dongfeng Chen, The Rausing Lab
"Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future."

Dr. Alexandra Segref, CECAD Cologne,Germay
"I am very satisfied with your product and costumer service. Bortezomib works very well in our assay, it is comparably cheaper than other inhibitors that we tested is more reliable for our assays. We see a great effect by using 10nM concentration."

R.B. Cambridge
"I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more."

Zhenghe John Wang Assistant Professor, Case Western Reserve University
"We have purchased LBH-589, Saha and MS-275 from you and they all worked well."

Jenny Sun
"We used the LBH-589 in our experiments. The compound is easy to use with excellent reproducibility."

Yu Wang, Harvard University
"The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research."

Philip Seeman, Toronto University
"Your LY404039 compound was well synthesized, its complicated stereochemical structure confirmed by NMR spectroscopy, and was biologically excellent in acting on brain dopamine receptors."

Dung-Fang Lee
"Based on our preliminary data, I found MLN8237 and VX-680 have good effects in inhibiting Aurka-maintaining ESC self-renewal in mouse ES cells."

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May 2010
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