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S1013
|
Bortezomib (Velcade) |
Bortezomib is a potent 20S proteasome inhibitor with Ki of 0.6 nM. |
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S2619
|
MG-132 |
MG-132 (ZLLLal) is potent inhibitor of proteasome with IC50 of 100 nM. |
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S2853
|
Carfilzomib (PR-171) |
Carfilzomib (PR-171) is a proteasome inhibitor with IC50 less than 5 nM. |
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S2181
|
MLN9708 |
MLN9708 is a selective inhibitor of chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM. |
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S2180
|
MLN2238 |
MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM, respectively. |
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S7172
|
ONX-0914 (PR-957) |
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S8066
|
Salinosporamide A (NPI-0052, Marizomib) |
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S7038
|
Epoxomicin (BU-4061T) |
Epoxomicin potently inhibits the chymotrypsin-like activity of the 20S proteasome. |
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S7049
|
Oprozomib (ONX 0912) |
Oprozomib (ONX 0912) selectively inhibits CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. |
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S1157
|
Delanzomib (CEP-18770) |
CEP-18770 is a potent chymotrypsin-like proteasome inhibitor with IC50 of 3.8 nM. |
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S1386
|
Nafamostat mesylate |
Nafamostat is an anticoagulant. |
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S3017
|
Aspirin (Acetylsalicylic acid) |
Aspirin is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. |
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S2101
|
Gabexate mesylate |
Gabexate is a serine protease inhibitor with IC50 of 0.19 μM which is used therapeutically in the treatment of pancreatitis and disseminated intravascular coagulation. |
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