MG-132

Catalog No.S2619

MG-132 Chemical Structure

Molecular Weight(MW): 475.62

MG-132 is an inhibitor of proteasome with IC50 of 100 nM in a cell-free assay, and also inhibits calpain with IC50 of 1.2 μM.

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In DMSO USD 100 In stock
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USD 170 In stock
USD 470 In stock
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Cited by 47 Publications

10 Customer Reviews

  • MDA-MB-231 cells were treated with 10 uM MG132 and incubated under normoxia or hypoxia for 4 h. Endogenous interaction between LATS2 and SIAH2 was analysed by immunoprecipitation.

    Nat Cell Biol 2015 17(1), 95-103. MG-132 purchased from Selleck.

    HeLa cells were transfected with control mimic, RMND5A siRNA or miR-138 mimic. After transfection for 36 h, cells were treated with proteasome inhibitor MG132 (20 uM) or Dimethyl sulfoxide (DMSO) for 8 h. Endogenous Exportin-5 protein and RMND5A protein expression was measured by western blotting.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

  • HeLa cells were transfected with negative control mimic, miR-138 mimic or RMND5A siRNA. After transfection for 36 h, cells were treated with MG132 (20 uM) or DMSO for 8 h. RMND5A and Exportin-5 protein expression were analyzed by immunocytochemistry. Nuclei were counterstained with DAPI.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

     

    TFEB induced autophagy dependent ATZ clearance in vitro. MEF transiently co-transfected with either ATZ plus GFP expressing plasmids or ATZ plus TFEB expressing plasmids were incubated with proteasome inhibitor MG132 or with DMSO for 6 h. Upon MG132 treatment, steady state levels of 52 kDa ATZ band increased in both cells transfected with ATZ plus GFP and with ATZ plus TFEB expressing plasmids. Quantification of band intensities showed a 48% reduction of ATZ in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP, in the absence of the proteasome inhibitor. In MG132 treated cells, a 61% decrease of ATZ was detected in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP.

    EMBO Mol Med 2013 5, 397-412. MG-132 purchased from Selleck.

  • JAK1 expression was analyzed in A375 cells expressing scrambled shRNA or shRNF125 (#2) and treated with MG132 (5 uM, 10 hr), and in Lu1205 cells expressing WT RNF125 and treated with MG132.

    Cell Rep 2015 11(9), 1458-73. MG-132 purchased from Selleck.

    LRB1 and LRB2 regulate phyB protein levels. PhyB protein levels in crude extracts from the wild type (WT) and the indicated mutant backgrounds were assayed by immunoblot analysis with anti-phyB monoclonal antibodies. Anti-PBA1 and anti-histone H3 antibodies were used to confirm equal protein loading. Rc-induced loss of phyB in the wild type is inhibited by 100 uM MG132.

    Plant Physiol 2012 60(1), 118-34. MG-132 purchased from Selleck.

  • Representative images for γ-H2AX-stained cells treated with 100 uM FA for 3 h without or with MG132. Fluorescence was measured in at least 50 nuclei in each of three experiments.

    Toxicol Appl Pharmacol 2015 286(2), 135-41. MG-132 purchased from Selleck.

    GSK-3β phosphorylation at Ser9 is enhanced in NOK-overexpressed stable cell lines. The proteasome inhibitor, MG132, was added in medium of HeLa-HA and HeLa-NOK-HA cells for 12 h and then the p-GSK-3b(Ser9) was assayed by western blotting.

    FEBS Lett 2012 586, 3787–3792. MG-132 purchased from Selleck.

  • Nek2A impedes SuFu ubiquitination. HEK293T cells transfected with Nek2A-Myc and Flag-SuFu for 48 h were treated with MG-132 to enrich ubiquitinated proteins, and subsequently subjected to co-immunoprecipitation assay. Precipitated proteins were probed using anti-Ub antibody.

    Int J Oncol, 2017, 50(2):373-380. MG-132 purchased from Selleck.

    Truncated mouse Period2 (Per2) protein was expressed in NIH3T3 cells, treated by cycloheximide with or without MG132 for 1-4 hours.Per2 was reported to be degraded by the proteasome proteolysis. By adding MG132 (25 μM), a proteasome inhibitor, the degradation of Per2 was dramatically decreased within 4 hours treatment (shown by western blot).

    2012 Dr. Edison DUKE-NUS Graduate Medical School Singapore.. MG-132 purchased from Selleck.

Purity & Quality Control

Choose Selective Proteasome Inhibitors

Biological Activity

Description MG-132 is an inhibitor of proteasome with IC50 of 100 nM in a cell-free assay, and also inhibits calpain with IC50 of 1.2 μM.
Targets
Proteasome [1]
(Cell-free assay)
100 nM
In vitro

MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM. MG-132 also inhibits calpain with IC50 of 1.2 μM. MG-132 induces neurite outgrowth in PC12 cells at an optimal concentration of 20 nM, displaying 500 times more potency than ZLLal. [1] MG-132 (10 μM) potently inhibits TNF-α-induced NF-κB activation, interleukin-8 (IL-8) gene transcription, and IL-8 protein release in A549 cells by inhibition of proteasome-mediated IκBα degradation. [2] MG-132 treatment potently induces p53-dependent apoptosis in KIM-2 cells by 26S proteasome inhibition. [3] Unlike BzLLLCOCHO or PS-341, MG-132 treatment results in weak inhibition of the chymotrypsinlike (CT-L) and peptidylglutamyl peptide hydrolysing (PGPH) activities of the 26S proteasome, whereas multiple myeloma cells (U266 and OPM-2) are more sensitive to induction of apoptosis by MG-132 than BzLLLCOCHO. [4] MG-132 (1 μM) sensitizes TRAIL-resistant prostate cancer cells by activating the AP-1 family members c-Fos and c-Jun, which, in turn, repress the antiapoptotic molecule c-FLIP(L). [5] MG-132 significantly enhances the ability of inositol hexakisphosphate (IP6) to reduce cellular metabolic activity in both PC3 and DU145 androgen-independent prostate cancer (AIPCa) cell lines. [6]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
LPS-stimulated RAW264.7 cells MXLGeY5kfGmxbjDBd5NigQ>? MWCyOUDPxE1? NF\MW2RFVVOR MmT1TY5pcWKrdIOgcol1emmlIH;4bYRmKHC{b3T1Z5Rqd25id3n0bEBKSzVyIH;mJFAvOSEQvF2= M{XwR|I1Pjl5NEm2
HL-60 MonNR5l1d3SxeHnjJGF{e2G7 M1HCblQxKM7:TR?= NXi5[JdmPDhiaB?= NIP4bGRFVVOR NU\GVHc2UUN3MEyxNEDPxE1? M1vLXlI1Pjl5NEm2
SMMC-7721 MYLDfZRwfG:6aXOgRZN{[Xl? NHy4XJY1OCEQvF2= MmHhOFghcA>? M1Pu[mROW09? Ml\TTWM2OD15LkGg{txO M4j2SVI1Pjl5NEm2
A-549 NXTZ[HBlS3m2b4TvfIlkKEG|c3H5 M2XmUVQxKM7:TR?= NHS3WY01QCCq M4DR[GROW09? MmDPTWM2ODxzMDFOwG0> NXez[YxiOjR4OUe0PVY>
MCF-7 NYnzeHFUS3m2b4TvfIlkKEG|c3H5 M2LyVFQxKM7:TR?= M1vFOVQ5KGh? MYPEUXNQ Ml:yTWM2OD15LkOg{txO MlrFNlQ3QTd2OU[=
SW-480 M4jZe2N6fG:2b4jpZ{BCe3OjeR?= MV[0NEDPxE1? NYnUfpJtPDhiaB?= M3XkeWROW09? MlzrTWM2OD12IN88US=> NW\LU4tQOjR4OUe0PVY>
NCI-H929 M2n4fGN6fG:2b4jpZ{BCe3OjeR?= NUfmPIRiOSEQvF2= NYfmNI9bPzJiaB?= NXzRO41CTE2VTx?= NHjYWZlKSzVyPUCuNVch|ryP MWKyOFYzPTB6OB?=
293T NUnkflBKS3m2b4TvfIlkKEG|c3H5 MlrHNVAh|ryP MkniO|IhcA>? NH\nVVlFVVOR MWfJR|UxRDJizszN MlnmNlQ3OjVyOEi=
293T M{XIZmZ2dmO2aX;uJGF{e2G7 M1j2elExKM7:TR?= NEPGVIMzPCCq MUDEUXNQ M3TMeG1w\GW{YYTlcJkhcW6mdXPld{Bp\WG2LYPoc4NsKCB? MoDhNlQ3OjVyOEi=
HeLa M1znXGtqdmG|ZTDBd5NigQ>? MXSxNEDPxE1? NGHtNFUyKGh? NHjKZYJFVVOR MnjUTY5lfWOnczDQRXJRKGOuZXH2ZYdmKGK7IHnubIljcXSrbnegdJJwe2Wjc3;t[UBi[3Srdnn0fS=> MlWxNlQ{OjF6M{O=
MDA-MB-231 NHj6e|JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIrHcpYyKM7:TR?= NITyNW04OiCq Ml\hSG1UVw>? MWfJR|UxRTBwMUig{txO M3XZZlI1OTV|MkC2
MCF-7 M{LrbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3HLc|Eh|ryP M370O|czKGh? NIriWZZFVVOR M3rwdWlEPTB;MD6xN{DPxE1? NHr3[3EzPDF3M{KwOi=>
MCF10A MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\4NUDPxE1? M4\BXlczKGh? MYLEUXNQ MYrJR|UxRTBwMkmg{txO Ml3pNlQyPTN{ME[=
HEK-293 M4C3TmtqdmG|ZTDBd5NigQ>? M2HvdVIh[W6mIEKwJO69VQ>? MWiyJIg> M4fOW2ROW09? MUDJcohq[mm2czDDbHQuVCCjY4Tpeol1gSC5aYToJGlEPTBib3[gPUBvVSB? NIjF[mUzOzV2MEe5NC=>
Calu6 NI[wZ4VHfW6ldHnvckBCe3OjeR?= MlOxNVAh|ryP NFTBRnEyQCCq NF;JVGZFVVOR NHnuT25UcWewaX\pZ4FvfGy7IHHjZ5VufWyjdHXzJIZz[XSjeHnuJJBz\WO3coPvdi=> NVjBUphWOjN3ME[0PFY>
IFN-gamma-induced RAW264.7 NV;aWWV2TnWwY4Tpc44hSXO|YYm= NHrhfY1FVVOR MnXwTY5pcWKrdIOgcol1emmlIH;4bYRmKHC{b3T1Z5Rqd25id3n0bEBKSzVyIH;mJFAvODd5IN88US=> MYeyNlI4PzJ5Nx?=
IPC227F MWPDfZRwfG:6aXOgRZN{[Xl? NIDTSYcyKM7:TR?= M1zWeFQ5KGh? M{T1XGROW09? MUjJR|UxRTBwMEe3JO69VQ>? NFy3cJEzOTl{NEWyPC=>
Hepa-1c1c7 MWPGeY5kfGmxbjDBd5NigQ>? NVWzOGppOjVizszN NFntWYY3KGh? Mlv4SG1UVw>? NWLrXGFVUW6lcnXhd4V{KE6{ZkKgdJJwfGWrbjDs[ZZmdA>? M{GzZ|IxOzl{NUS0
COS-7 NXXa[5RkS3m2b4TvfIlkKEG|c3H5 NF3lZ|YyOCEQvF2= MX3EUXNQ NYTQbGZWUUN3MEyxNEDPxE1? NX30SnIxOThyOEiwPVc>
HuH-7 Mn3OR5l1d3SxeHnjJGF{e2G7 MVOxNEDPxE1? NVLmeFBvTE2VTx?= NWHjXphSUUN3MEyxNEDPxE1? NYjne|NVOThyOEiwPVc>
OCI-Ly3 MYrGeY5kfGmxbjDBd5NigQ>? M2fC[|ExKM7:TdMg NEnvSIo1KGh? NXvvPWRxTE2VTx?= NIHhWYdKdmS3Y3XzJIh2dWGwIFnrZZBx[UKjbIDoZUB{fGGkaXzpfoF1cW:wIIfpeIghTUN3MDDv[kAyKM7:TR?= NV;HUW1zOThyMkSxNVM>
A2780 cDDP MonhRZBweHSxc3nzJGF{e2G7 NVK4U2V5OjRiaB?= NHHRfm9FVVOR NWDnSIoyUW6mdXPld{BieG:ydH;zbZMh[nliaX7obYJqfGmwZzDQWGVPKGSnZ4Lh[IF1cW:w M{TNNlE4Pjh2MEG4
LPS-stimulated RAW264.7 cells NFL2PHVHfW6ldHnvckBCe3OjeR?= MX\EUXNQ MleyTY5pcWKrdIOgUmYuc2GycHHCJGRPSSCkaX7kbY5o MYOxO|QxPzJ5Nx?=
PC12 MYDGeY5kfGmxbjDBd5NigQ>? MkPHNVAxKM7:TdMg NHnUenczPCCq NXLIOphZTE2VTx?= MYjJcohq[mm2czC2MW9JTEFvIHHu[EBJOk9{LXnu[JVk\WRiY4n0c5RwgGmlaYT5 M4jMRVE4OTV6NEW0
PC3 NFTYWodIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWfWVXJOOjBizszN NE\tVGM1QCCq MV\EUXNQ MULJR|UxRTBwNjFOwG0> M1TWZ|E3Pjh4NUO3
LP-1 M3:w[2Fxd3C2b4Ppd{BCe3OjeR?= MkXNN|AxKG6P NInROXMzPCCq MXzEUXNQ NXW1XItbUW6mdXPld{BieG:ydH;zbZMh[nliaX7jdoVie2mwZzDjcIVifmWmIGDBVnAhdGW4ZXygZY5lKHKnZIXjbY5oKE2lbD2xJJBzd3SnaX6gcIV3\Wx? M3vrSFE2QTV6NUi5
ES6 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWHxUHV5UUN3ME2wMlAyOzB4IN88US=> M3zYUXNCVkeHUh?=
A101D NITJWHRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\UTGlEPTB;MD6wN|I4QSEQvF2= MnW0V2FPT0WU
OCUB-M MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV\PTWZtUUN3ME2wMlA{PzN5IN88US=> MmjFV2FPT0WU
LB2518-MEL MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTBwMEO3OkDPxE1? M1rWenNCVkeHUh?=
SH-4 NFv1eXRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX;JR|UxRTBwMESzNUDPxE1? NYnVeVBoW0GQR1XS
KNS-42 M2fa[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1uzTGlEPTB;MD6wOFQ1OSEQvF2= NELwWINUSU6JRWK=
DSH1 Ml3BS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWTJR|UxRTBwMEWyPFkh|ryP NV3iTmhKW0GQR1XS
NTERA-S-cl-D1 NVrrPJFjT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mk\jTWM2OD1yLkC1O|czKM7:TR?= NV7QelFbW0GQR1XS
D-542MG M3XxeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmjxTWM2OD1yLkC1PVU4KM7:TR?= NGjCcW9USU6JRWK=
KS-1 NFHseZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HjcGlEPTB;MD6wOlQ2QCEQvF2= NVnlc|FiW0GQR1XS
BL-41 M2nCeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3y3ZWlEPTB;MD6wOlk1PyEQvF2= NIrrSXRUSU6JRWK=
LXF-289 MkDhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3vtW2lEPTB;MD6wO|A3PiEQvF2= MYnTRW5ITVJ?
D-247MG NWq1WlJVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGXSNJRKSzVyPUCuNFczODlizszN MXvTRW5ITVJ?
MMAC-SF MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWLJR|UxRTBwMEeyOlgh|ryP NGTRfXRUSU6JRWK=
CP66-MEL NIjFN|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGTzd3hKSzVyPUCuNFc2KM7:TR?= MX3TRW5ITVJ?
LB771-HNC MoHYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXZVmZPUUN3ME2wMlA5ODN4IN88US=> NXzmdZo2W0GQR1XS
no-10 M{ixTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{DoPWlEPTB;MD6wPFkxQSEQvF2= M3XsfHNCVkeHUh?=
A388 NXewXW53T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXnkRo96UUN3ME2wMlA6ODZ3IN88US=> MoPIV2FPT0WU
OPM-2 M17lV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWXJR|UxRTBwMUC0O|Qh|ryP NEXkeXJUSU6JRWK=
OVCAR-4 M3fEVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnvpTWM2OD1yLkGwPVM5KM7:TR?= NHPlbIVUSU6JRWK=
HOP-62 NU\CVFJUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYrJR|UxRTBwMUC5OFkh|ryP MmnxV2FPT0WU
ML-2 NULHelR3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlzyTWM2OD1yLkGxPFA3KM7:TR?= NHf4SVJUSU6JRWK=
UACC-257 NXnhU|g6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlSzTWM2OD1yLkGxPVI4KM7:TR?= NVzSUpI5W0GQR1XS
NEC8 NUH6S4tbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4W1eGlEPTB;MD6xNVk6PSEQvF2= NYn6OWpWW0GQR1XS
ONS-76 M4PDT2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4nMPGlEPTB;MD6xNlk{PSEQvF2= MVfTRW5ITVJ?
KE-37 M{HzS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTBwMUOyO|gh|ryP NIDCbJNUSU6JRWK=
HT-144 MnXLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTBwMUO4PVUh|ryP MmTWV2FPT0WU
LB2241-RCC MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVz3W4RYUUN3ME2wMlE1OjR5IN88US=> MnXYV2FPT0WU
TE-5 NUDPOppxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M17P[2lEPTB;MD6xOFI4QCEQvF2= MkHrV2FPT0WU
KINGS-1 NVfneYNmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NI\WT5hKSzVyPUCuNVQ4QSEQvF2= NFXVfVdUSU6JRWK=
NCI-H69 NVTxTJNoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2XhN2lEPTB;MD6xOVE1OSEQvF2= Mln4V2FPT0WU
CAS-1 NVrXVI1FT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH24ZmZKSzVyPUCuNVU1QDJizszN M2Plc3NCVkeHUh?=
D-263MG MnfmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEHN[|dKSzVyPUCuNVYxODZizszN Ml7MV2FPT0WU
A253 NHHm[o5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4PEeWlEPTB;MD6xOlEzQCEQvF2= Ml;EV2FPT0WU
PF-382 MUfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWXpfWRbUUN3ME2wMlE3PzB4IN88US=> MoeyV2FPT0WU
CESS MljrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlPnTWM2OD1yLkG3NFYh|ryP NEe2NZBUSU6JRWK=
MZ2-MEL NXGxTGVpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M321R2lEPTB;MD6xO|U2QSEQvF2= M2\wOHNCVkeHUh?=
HEL NXmxZ5NyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4HhS2lEPTB;MD6xPFUyPyEQvF2= MVHTRW5ITVJ?
D-392MG NUPGfopMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXX2fFdDUUN3ME2wMlE6OTF3IN88US=> NUjMZ4pjW0GQR1XS
SK-LMS-1 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3S0T2lEPTB;MD6xPVMxOyEQvF2= M{mxbnNCVkeHUh?=
GI-ME-N NYHLZ5BPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2XmO2lEPTB;MD6xPVMxPiEQvF2= M4LQbnNCVkeHUh?=
LB831-BLC M1PvXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUDJR|UxRTBwMUmzOEDPxE1? MYLTRW5ITVJ?
DU-4475 MmexS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4PEWGlEPTB;MD6xPVY2QCEQvF2= NIHHcoRUSU6JRWK=
IST-SL1 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYD0UmhOUUN3ME2wMlIxODl2IN88US=> MWPTRW5ITVJ?
GAK M1vSUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXTJR|UxRTBwMkC1N|Qh|ryP NV7WVldsW0GQR1XS
EW-1 NYrpWW5MT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWTJR|UxRTBwMkGwOFch|ryP M4jkZXNCVkeHUh?=
LAMA-84 NWPyUI1VT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4Do[WlEPTB;MD6yNVg2OSEQvF2= MXLTRW5ITVJ?
SK-UT-1 NFSzUnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV;JR|UxRTBwMkKwOFkh|ryP MYPTRW5ITVJ?
VA-ES-BJ MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnLVTWM2OD1yLkKyNlU4KM7:TR?= Mny2V2FPT0WU
ACN MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTBwMkK2N|gh|ryP MnLmV2FPT0WU
SK-PN-DW M{TNdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHTwdVRKSzVyPUCuNlMyQSEQvF2= NGqzcJNUSU6JRWK=
HD-MY-Z M3raXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M33SfWlEPTB;MD6yN|MxOyEQvF2= NYHicYppW0GQR1XS
LB373-MEL-D NX;QOYJRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3r0dmlEPTB;MD6yOFE6QCEQvF2= M2nWRnNCVkeHUh?=
COLO-829 NF6yPG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFvnWmpKSzVyPUCuNlQzPTdizszN MXHTRW5ITVJ?
ES8 M{[3Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTBwMkS3OlMh|ryP NFfv[5hUSU6JRWK=
RXF393 NELUcVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXZbmd{UUN3ME2wMlI2ODF3IN88US=> NYrTPI9NW0GQR1XS
TK10 M2WzPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2\CZmlEPTB;MD6yOVQ{PSEQvF2= NHraO2dUSU6JRWK=
LOUCY NXfJVHZkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVPJR|UxRTBwMkW0OVYh|ryP M2rs[XNCVkeHUh?=
MZ7-mel NHP4OHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUnEUpNqUUN3ME2wMlI3Ozd2IN88US=> Ml7CV2FPT0WU
CP67-MEL MmDBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIHFRYRKSzVyPUCuNlY4OyEQvF2= MoLEV2FPT0WU
C2BBe1 M4PabWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGr2doRKSzVyPUCuNlc6ODdizszN MYPTRW5ITVJ?
K052 NF23TotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoG5TWM2OD1yLkK4PVkh|ryP M{jFRXNCVkeHUh?=
MOLT-16 NUnSe|U3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWToOVIzUUN3ME2wMlI6PTJ2IN88US=> MVvTRW5ITVJ?
KNS-81-FD MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVTJR|UxRTBwM{CzNlMh|ryP NVW5N|FHW0GQR1XS
CMK MmL1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjob2R5UUN3ME2wMlMyOTJizszN NXfZPW1kW0GQR1XS
LAN-6 Mnu2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NImyXYpKSzVyPUCuN|E{KM7:TR?= MWDTRW5ITVJ?
KLE MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MojGTWM2OD1yLkOxN|A3KM7:TR?= M4DWWHNCVkeHUh?=
NCCIT MoHaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmfsTWM2OD1yLkOxO|g{KM7:TR?= NYLnT4NwW0GQR1XS
HH MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHTPeXhKSzVyPUCuN|I5QTdizszN NX60NHpYW0GQR1XS
TE-8 NGPrfoFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlzRTWM2OD1yLkO0Nlc6KM7:TR?= NVjRU3hKW0GQR1XS
GDM-1 NETmdFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M13NeGlEPTB;MD6zOVExPCEQvF2= M4H5R3NCVkeHUh?=
NCI-H747 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVXtdFRzUUN3ME2wMlM4OTB|IN88US=> NUOxVnp1W0GQR1XS
NCI-H1092 NUDZcGNlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{mzW2lEPTB;MD6zPFg1PCEQvF2= MkmyV2FPT0WU
8-MG-BA MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYnQN2l{UUN3ME2wMlM6QDN5IN88US=> MnHPV2FPT0WU
NB17 NHvBSXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlfuTWM2OD1yLkSyPVch|ryP NVXGbYhMW0GQR1XS
LC4-1 NXnYe|JKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1judmlEPTB;MD60N|YxPyEQvF2= NF;yOFZUSU6JRWK=
TE-1 M4qxSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3HYSmlEPTB;MD60OVEyQSEQvF2= NV3YZml[W0GQR1XS
KALS-1 M{TEbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPnSY5KSzVyPUCuOFY2QDRizszN NGT0fFRUSU6JRWK=
CCRF-CEM MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4L0cGlEPTB;MD60O|Y4PCEQvF2= NXfMZYlQW0GQR1XS
OS-RC-2 M4nxRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXPqblVCUUN3ME2wMlQ4QTd{IN88US=> MWPTRW5ITVJ?
A704 MljmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MV7JR|UxRTBwNEi2PVIh|ryP NGmwcplUSU6JRWK=
BB49-HNC MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH2xOGhKSzVyPUCuOFkxQTZizszN M{\FeXNCVkeHUh?=
EVSA-T M4\lNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvmXZhKSzVyPUCuOFk6OTFizszN NILDZ5pUSU6JRWK=
Mo-T NXjYd3Y6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVLJR|UxRTBwNUG3OlIh|ryP MWnTRW5ITVJ?
MONO-MAC-6 NEjzOFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTBwNUO2NVEh|ryP MmrRV2FPT0WU
BB65-RCC NUfKcoNrT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHXsdZdKSzVyPUCuOVY5OTFizszN MkXZV2FPT0WU
NCI-H1882 M4DXWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2WxNmlEPTB;MD61PVA{PiEQvF2= MnXxV2FPT0WU
TE-9 M33xPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1TmOGlEPTB;MD62NVA{OyEQvF2= MWjTRW5ITVJ?
NCI-H2126 MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYnJR|UxRTBwNkK2Olkh|ryP NInBfHRUSU6JRWK=
SF268 MmrNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUjJR|UxRTBwNkW2OFEh|ryP MmfrV2FPT0WU
SW872 MnXVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYLBU2FUUUN3ME2wMlY2PzJ7IN88US=> M3G0PHNCVkeHUh?=
LS-513 MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3T4RWlEPTB;MD62Olc2OSEQvF2= MYDTRW5ITVJ?
NCI-H1355 M3TxSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2LrOmlEPTB;MD62PFYyQSEQvF2= MmGwV2FPT0WU
BL-70 M1;mS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH\W[plKSzVyPUCuOlk{QDhizszN NWfYdXpzW0GQR1XS
NCI-SNU-5 M4\1UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3HHZmlEPTB;MD62PVU1PSEQvF2= NYPNUIVuW0GQR1XS
SNU-C2B MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjpTWM2OD1yLkewO|M6KM7:TR?= NWi4UmtkW0GQR1XS
GB-1 NWHzNJVtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoTRTWM2OD1yLkeyNVI1KM7:TR?= Ml;tV2FPT0WU
CTB-1 MmrrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIrz[pZKSzVyPUCuO|c6PTVizszN MmnJV2FPT0WU
Becker MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFPEfWJKSzVyPUCuO|k3OjFizszN MV3TRW5ITVJ?
KM12 NHTPUW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{nlWGlEPTB;MD64OVQ3PiEQvF2= MXLTRW5ITVJ?
ES7 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGTBT2lKSzVyPUCuPFk3PSEQvF2= MmTMV2FPT0WU
COLO-684 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlizTWM2OD1yLkmwOlU5KM7:TR?= M1nQeXNCVkeHUh?=
HCC2998 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoL1TWM2OD1yLkmzPFU1KM7:TR?= NG[2NFlUSU6JRWK=
TE-10 M1LFNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnrKTWM2OD1yLkm2OFMh|ryP NGDqcHdUSU6JRWK=
SF126 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFv5boZKSzVyPUCuPVg6PzFizszN NGHwZpdUSU6JRWK=
EKVX M3vYdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4PiUmlEPTB;MT6wN|Q1OiEQvF2= NUjsUmRUW0GQR1XS
KARPAS-45 M2nkS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH2zZpJKSzVyPUGuNFQxOTZizszN MnfDV2FPT0WU
KGN NV\k[YRST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIPKVW5KSzVyPUGuNFUxPDVizszN Mnq1V2FPT0WU
ES1 NX\ue4IzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX74TI9EUUN3ME2xMlA4QTJzIN88US=> M1K0SXNCVkeHUh?=
L-540 M4fLcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVf4dVhuUUN3ME2xMlEyQDN7IN88US=> M17ISnNCVkeHUh?=
KURAMOCHI MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVfJR|UxRTFwMUKzO|Qh|ryP Mk\5V2FPT0WU
LU-65 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX7JR|UxRTFwMUK3OVMh|ryP M4ftXXNCVkeHUh?=
MFH-ino NV7Rd5pZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXnJR|UxRTFwMUe1NFEh|ryP MojtV2FPT0WU
NCI-H23 Ml73S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3f1NGlEPTB;MT6yNFQyKM7:TR?= NFGwOWlUSU6JRWK=
IA-LM MlzLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGDxR|BKSzVyPUGuNlQyOTZizszN MoXIV2FPT0WU
PSN1 MnrCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1y4[2lEPTB;MT6yO|AyPiEQvF2= MYLTRW5ITVJ?
NCI-H719 NGnDS4dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NILxSIhKSzVyPUGuNlc1OTFizszN M4ThfHNCVkeHUh?=
SW684 NEXYNnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUDHTJU5UUN3ME2xMlI5PjV7IN88US=> NFjZN3JUSU6JRWK=
HCE-4 Ml7qS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWHJR|UxRTFwM{CyNlEh|ryP MUHTRW5ITVJ?
EW-16 MortS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnQR4ljUUN3ME2xMlMyOzR5IN88US=> NGrlTXRUSU6JRWK=
NCI-H128 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn31TWM2OD1zLkO1PFE1KM7:TR?= MoXLV2FPT0WU
HC-1 MljqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLNTWM2OD1zLkO4NVch|ryP NYnyUlRwW0GQR1XS
IST-MES1 M3nGW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LpcGlEPTB;MT60NFIxQCEQvF2= MoD1V2FPT0WU
Raji M{KwfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEfLR|RKSzVyPUGuOFE5PSEQvF2= MonWV2FPT0WU
DMS-114 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWfJR|UxRTFwNES1N|kh|ryP NHq2NHRUSU6JRWK=
GI-1 M2XQfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVvJR|UxRTFwNEexN|Eh|ryP MWHTRW5ITVJ?
NCI-H2081 MkDZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\Kcm54UUN3ME2xMlU2OTl4IN88US=> NH;rd2ZUSU6JRWK=
LC-1F NV;HW3I{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF3ofHZKSzVyPUGuOVUyQThizszN MUHTRW5ITVJ?
NCI-H2227 MmHFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWfEdHBpUUN3ME2xMlYyPTZzIN88US=> NW\aT2dXW0GQR1XS
D-502MG NVXTR4xpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWj2SXRQUUN3ME2xMlY4OjFzIN88US=> MWPTRW5ITVJ?
NCI-H2141 M1rvVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnfxTWM2OD1zLk[3N|E4KM7:TR?= M4nkWXNCVkeHUh?=
LS-411N NYqzSoRST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVHIUXBVUUN3ME2xMlY6QDB5IN88US=> M33XfnNCVkeHUh?=
SU-DHL-1 NHroVoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DJfWlEPTB;MT63NVI5OSEQvF2= Mn[3V2FPT0WU
BB30-HNC MoLwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{\wWWlEPTB;MT63NlY5PSEQvF2= M4PBc3NCVkeHUh?=
TE-15 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3zoZWlEPTB;MT65NlM4OyEQvF2= NYrqPFluW0GQR1XS
JVM-3 NIPNdpJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXPJR|UxRTFwOUO5NFQh|ryP M17t[XNCVkeHUh?=
IST-SL2 NV\6PHdlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{nYNmlEPTB;Mj6wNVI2OiEQvF2= NWLJe|NQW0GQR1XS
EW-18 NUXRTmpQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnSzTWM2OD1{LkCyN|M4KM7:TR?= NVf1eHlPW0GQR1XS
DJM-1 M1H1dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4OxbWlEPTB;Mj6wNlU2OiEQvF2= NEG5dZFUSU6JRWK=
no-11 NE\iT2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmraTWM2OD1{LkCzNVA1KM7:TR?= M13MOXNCVkeHUh?=
QIMR-WIL MojNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4DGfmlEPTB;Mj6xOlc3OiEQvF2= M1jBRXNCVkeHUh?=
MC-CAR NXjsbmFnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUPJR|UxRTJwMkK5OUDPxE1? MnzOV2FPT0WU
KM-H2 Ml\IS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnvvTWM2OD1{LkK5NFQ{KM7:TR?= Moj1V2FPT0WU
ECC12 NFfNWm1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXjPW3VOUUN3ME2yMlM4QTRizszN MoDrV2FPT0WU
HCE-T NX:0PYo1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHUTWM2OD1{LkS0PFg{KM7:TR?= NIPFPXFUSU6JRWK=
MFM-223 NF31NGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFPN[4hKSzVyPUKuOVA5PzFizszN MlXwV2FPT0WU
SW982 MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTJwNUG0PEDPxE1? NXzvfWlQW0GQR1XS
KG-1 Mn\oS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzaNnpKSzVyPUKuPFg4QTFizszN NF7hT|VUSU6JRWK=
ES4 NED5OYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF3KbYFKSzVyPUOuNFYyOTFizszN M4O5NnNCVkeHUh?=
SCC-3 NYHT[owyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NULibog3UUN3ME2zMlExQDR6IN88US=> M2PaPHNCVkeHUh?=
RH-1 MnXvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlzpTWM2OD1|LkO4O|Q5KM7:TR?= NUXTdmdGW0GQR1XS
NCI-H748 NXH5U2d5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnTvTWM2OD1|LkS0NlY3KM7:TR?= MnzCV2FPT0WU
HCC2218 NXvYW5pFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MW\JR|UxRTNwNE[5N|ch|ryP MV3TRW5ITVJ?
MEG-01 NEHKfYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoDQTWM2OD1|LkW5Olgh|ryP M2mzNXNCVkeHUh?=
NB12 NUT1fWh1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M322d2lEPTB;Mz61PVg5QCEQvF2= Ml[yV2FPT0WU
SNB75 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYrSRZZTUUN3ME2zMlYxOTB|IN88US=> NGLBSFdUSU6JRWK=
KMS-12-PE NIjQV3FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NET2NWdKSzVyPUOuOlc4OjNizszN M4WxbnNCVkeHUh?=
SKM-1 NGDhTWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIXs[YdKSzVyPUOuO|E{PzZizszN NYizUoI3W0GQR1XS
COLO-320-HSR MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnzTVJ2UUN3ME2zMlc2PjN2IN88US=> NU\m[mhVW0GQR1XS
NKM-1 MnX2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIG3VnRKSzVyPUOuO|c{PzhizszN NEKwOoRUSU6JRWK=
TE-6 NX7hO4pqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnrVTWM2OD1|Lkm0OVYyKM7:TR?= M1u5THNCVkeHUh?=
D-336MG MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGPCVmhKSzVyPUSuNFEyPjZizszN MlrEV2FPT0WU
NCI-H1650 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnroTWM2OD12LkG1O|k4KM7:TR?= NXHJNY1WW0GQR1XS
ES3 NYXXSlBtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmDqTWM2OD12LkOyPFI1KM7:TR?= M4Tp[nNCVkeHUh?=
YT NVPKXZdnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MX7JR|UxRTRwM{W0NlQh|ryP Mn3MV2FPT0WU
ES5 NXLVb5FHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUHJR|UxRTRwNECyOVUh|ryP NX7XeG1oW0GQR1XS
LB647-SCLC NXTMOGR7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTRwNU[zNFgh|ryP MnnRV2FPT0WU
HAL-01 M2DMSWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2TVUmlEPTB;ND61O|A{PCEQvF2= M1PsO3NCVkeHUh?=
LP-1 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHP6W4ZKSzVyPUSuO|I{PzFizszN MkPMV2FPT0WU
BC-1 M3TlR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4TEWmlEPTB;NT6wNFQ1PyEQvF2= NFG3dnpUSU6JRWK=
EB-3 NXT1UWJXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{L1R2lEPTB;NT6wN|A1OSEQvF2= NX;tPFdWW0GQR1XS
GT3TKB NY\RRYJbT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVfJR|UxRTVwMUe2OlIh|ryP Ml[zV2FPT0WU
NCI-H209 NXXrU3ZkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIHGd2NKSzVyPUWuNVk{PTJizszN NIjjTHVUSU6JRWK=
BT-474 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXHJR|UxRTVwMkOxNFIh|ryP NX3SOXQ6W0GQR1XS
RKO M2WxVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MX7JR|UxRTVwMkO0NlIh|ryP NHO0ZY5USU6JRWK=
SIMA NUjyTJpmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{TPfWlEPTB;NT6zNFc3PSEQvF2= MWfTRW5ITVJ?
RL NGXHUJVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUDJR|UxRTVwM{e1OFEh|ryP MoDGV2FPT0WU
GCIY MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmCwTWM2OD13LkS3NlM3KM7:TR?= M3XQVnNCVkeHUh?=
Calu-6 NUPG[XBXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2LFXmlEPTB;NT62NlIh|ryP MVnTRW5ITVJ?
ALL-PO NF24eXdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXL1W5BkUUN3ME21MlY{Pzl3IN88US=> M4nLUnNCVkeHUh?=
ARH-77 NUfle3FUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTVwNkewPFch|ryP NXvwZVdZW0GQR1XS
A4-Fuk NHT6PVFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4TsNWlEPTB;Nj6wPFEyQCEQvF2= NWPMW5BqW0GQR1XS
NCI-H1581 NILjWlVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVjLepdoUUN3ME22MlI{QDR7IN88US=> MV;TRW5ITVJ?
HUTU-80 NYKzOndET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4O5bWlEPTB;Nj6zOlg6PyEQvF2= NW\CNHBXW0GQR1XS
TGW NYnDXFF1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2S4fmlEPTB;Nj60OVU6OyEQvF2= MYrTRW5ITVJ?
SK-N-FI NXfRR5UxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFLFSWNKSzVyPU[uOFU5PTRizszN MlriV2FPT0WU
U-266 NH3m[WlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXmN|lJUUN3ME22MlUyQTJ4IN88US=> NGHnSpJUSU6JRWK=
EM-2 Mn3CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmnvTWM2OD14Lk[3NFk6KM7:TR?= M3PZZnNCVkeHUh?=
NMC-G1 NWHuPYJHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXfHVJdzUUN3ME22MlcyQDl3IN88US=> MkH5V2FPT0WU
KASUMI-1 MnL6S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnTQTWM2OD14Lki0O|g4KM7:TR?= NVPE[IV3W0GQR1XS
NALM-6 M3Ptfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4T5c2lEPTB;Nj64Olc2PCEQvF2= MV;TRW5ITVJ?
OCI-AML2 NWfhbWJIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2C5VGlEPTB;Nz6wNFMzPiEQvF2= M{jzdXNCVkeHUh?=
SHP-77 NH3SbVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlv3TWM2OD15LkKyOFMh|ryP M4rpeHNCVkeHUh?=
NOMO-1 NXPWWmU4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MljNTWM2OD15LkK0NlU1KM7:TR?= M3v1NHNCVkeHUh?=
SK-N-DZ MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXvwWnJHUUN3ME23MlcyODh7IN88US=> NWTvV2VzW0GQR1XS
LB1047-RCC NHu4fmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEPifHNKSzVyPUeuO|IzOzFizszN M2Kx[XNCVkeHUh?=
MZ1-PC NYCyTGpDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnSxTWM2OD15Lki2OVU5KM7:TR?= MlvGV2FPT0WU
NB10 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEfvfolKSzVyPUeuPVk2PTZizszN M1HOb3NCVkeHUh?=
RL95-2 NVTZUHlsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUDJR|UxRThwMUC4OFIh|ryP M2fDdnNCVkeHUh?=
OMC-1 NHHJPIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHPLNYlKSzVyPUiuOVIyQTFizszN MVrTRW5ITVJ?
D-283MED MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3\ubmlEPTB;OD65NVcyQSEQvF2= MVrTRW5ITVJ?
MC116 M2nLfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jnSGlEPTB;OD65O|k1KM7:TR?= Mn\tV2FPT0WU
SJSA-1 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;XZVFuUUN3ME25MlA6ODlzIN88US=> MlHpV2FPT0WU
JiyoyeP-2003 NV7pXVVzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWHJR|UxRTlwMkmzNVch|ryP NYjpVJkyW0GQR1XS
IST-MEL1 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fTdmlEPTB;OT63OFE6QCEQvF2= M4nKNnNCVkeHUh?=
CTV-1 MoTzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWfJR|UxRTFyLkC5O|kh|ryP M1XnenNCVkeHUh?=
NH-12 NVfJZ4lST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmrLTWM2OD1zMD6yOFM{KM7:TR?= M4fnSXNCVkeHUh?=
CA46 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWDXeppZUUN3ME2xNE4{PjFizszN MWXTRW5ITVJ?
NCI-SNU-1 NX\sRVl6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVTuSGFSUUN3ME2xNE41QTZ7IN88US=> M{jWZ3NCVkeHUh?=
SCLC-21H NGG3O4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{LWS2lEPTB;MUCuOlU6PiEQvF2= MnSwV2FPT0WU
EC-GI-10 NYrGfJNvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{jHbGlEPTB;MUCuO|A{OSEQvF2= MljEV2FPT0WU
SR NVvjNHFRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3\pNmlEPTB;MUGuNFE5PSEQvF2= NXnDNGw1W0GQR1XS
NCI-H1648 NVvRfo11T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXPJR|UxRTFzLkC5OlUh|ryP M1jZUHNCVkeHUh?=
TGBC1TKB M1jrd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{jQeGlEPTB;MUGuOFExOiEQvF2= M33VfHNCVkeHUh?=
EW-11 MlvsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVLwVnJRUUN3ME2xNU42OTh4IN88US=> M3TaPXNCVkeHUh?=
SK-MM-2 M4Dnfmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml:5TWM2OD1zMT64NFYyKM7:TR?= NH:2cXVUSU6JRWK=
NCI-H524 NEexcnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGn1SpdKSzVyPUGxMlk5OjJizszN MlXDV2FPT0WU
NOS-1 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVfZ[pZQUUN3ME2xNk4xOzR3IN88US=> MYDTRW5ITVJ?
AM-38 MkHSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HPbGlEPTB;MUKuOVY{OyEQvF2= MV3TRW5ITVJ?
A498 M4DuZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkXOTWM2OD1zMj63NFY6KM7:TR?= NIfKRo9USU6JRWK=
KARPAS-422 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3TmTmlEPTB;MUKuO|Q6PiEQvF2= MlfEV2FPT0WU
LU-139 NHX2TXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DnPGlEPTB;MUKuPVAzPiEQvF2= NVS5eWNyW0GQR1XS
COR-L88 MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTF{LkmzPFIh|ryP NUfYO4s1W0GQR1XS
K5 NXPnWY1yT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{P4XWlEPTB;MUKuPVQ3OiEQvF2= Ml7pV2FPT0WU
NB13 NEfSZY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFL2dIJKSzVyPUGyMlk4QDNizszN MVTTRW5ITVJ?
MRK-nu-1 Mo\0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlLvTWM2OD1zMz6xPVUh|ryP MYPTRW5ITVJ?
MHH-NB-11 Mor0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3m3R2lEPTB;MUOuNlkxOiEQvF2= MXPTRW5ITVJ?
KU812 NYDRO4F2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPrb3V4UUN3ME2xN{43OTJ2IN88US=> MX3TRW5ITVJ?
TE-12 M1XndGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NW\QSpJYUUN3ME2xN{43QTl2IN88US=> MUHTRW5ITVJ?
NCI-N87 NV7xVokyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2jzZWlEPTB;MUOuO|M3KM7:TR?= MYPTRW5ITVJ?
EB2 NIX5[o5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVPJR|UxRTF|Lki1NFUh|ryP MmLBV2FPT0WU
DB NIL5ZWJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkHNTWM2OD1zMz65PFg2KM7:TR?= MX7TRW5ITVJ?
697 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTF2LkS1NVEh|ryP MlrWV2FPT0WU
MSTO-211H Mn;pS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2qybWlEPTB;MUSuO|Q1QCEQvF2= M13mVnNCVkeHUh?=
JVM-2 NGjQU29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjlTWNtUUN3ME2xOE44PzN3IN88US=> MX;TRW5ITVJ?
COLO-824 MkLmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfoRWVKSzVyPUG0Mlc6QTRizszN MlfXV2FPT0WU
BC-3 M1HFOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{i5Z2lEPTB;MUWuN|k5KM7:TR?= NXr5XVZyW0GQR1XS
BOKU NHzN[JhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFz2SWVKSzVyPUG1Mlk3ODhizszN NYLRPJNKW0GQR1XS
GOTO MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHjvSolKSzVyPUG2Mlk3OTdizszN NEnlPWpUSU6JRWK=
HCC2157 Ml3JS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HCV2lEPTB;MUeuOFc2PSEQvF2= NXjNXoNzW0GQR1XS
LS-1034 Mk\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn;kTWM2OD1zNz62PFE5KM7:TR?= MmPaV2FPT0WU
CAL-148 NGjSPFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4S1Z2lEPTB;MUeuPVc6PiEQvF2= MlvSV2FPT0WU
MOLT-4 MnnVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVXOOpBwUUN3ME2xPE45OjB6IN88US=> MYjTRW5ITVJ?
Daudi MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHTFZmpKSzVyPUG4MlkzOzFizszN NIDhbIFUSU6JRWK=
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KMOE-2 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTF7Lk[0PFIh|ryP MV\TRW5ITVJ?
HL-60 M1\mUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml7lTWM2OD1{MD6xPVY2KM7:TR?= NXXoV|l4W0GQR1XS
P31-FUJ NUHtdFlpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHqxNnVKSzVyPUKwMlQ4PTNizszN MXjTRW5ITVJ?
IM-9 MoTNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkH0TWM2OD1{MD62NlI1KM7:TR?= NYHJU49LW0GQR1XS
HDLM-2 NUPSR5VDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnTTTWM2OD1{MD64PFIyKM7:TR?= NXnXOGZDW0GQR1XS
NCI-H1304 MoiyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVnGPIFCUUN3ME2yNU4xOzFzIN88US=> MlvOV2FPT0WU
NCI-H345 NYLw[W5HT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTJzLkC2OFMh|ryP NWjLcYhHW0GQR1XS
RPMI-6666 NFXXN5FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlvjTWM2OD1{MT6zOlAzKM7:TR?= MX\TRW5ITVJ?
GR-ST Mn7SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1XVfmlEPTB;MkGuOFE4KM7:TR?= MULTRW5ITVJ?
CHP-126 M{DkVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVvLT|NDUUN3ME2yNU43OThzIN88US=> NWnhNG1{W0GQR1XS
EHEB MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUHJR|UxRTJzLk[3N|Eh|ryP NEOxZ2tUSU6JRWK=
CPC-N M1jqPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3W1N2lEPTB;MkSuNFIxOSEQvF2= MlOxV2FPT0WU
NB1 M33OUmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYTacJJ2UUN3ME2yOE43QTN7IN88US=> NHfiOYJUSU6JRWK=
LS-123 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2HjUWlEPTB;MkSuPVAyOiEQvF2= NGTmUIRUSU6JRWK=
ST486 M3i2eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{\xUmlEPTB;MkWuNVEyOyEQvF2= NWTBdG13W0GQR1XS
NCI-H1963 M33jZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2fvR2lEPTB;Mk[uNFYzOyEQvF2= NFO0TI9USU6JRWK=
U-87-MG M3PMWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{Di[mlEPTB;Mk[uO|Y1PCEQvF2= M3;NdnNCVkeHUh?=
COR-L279 NVG2eGQxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF7tXJlKSzVyPUK2Mlc6OjJizszN NEToOY5USU6JRWK=
LU-165 NHLUUoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3;BV2lEPTB;MkiuNFg3OSEQvF2= NGK2cYxUSU6JRWK=
COLO-800 M2\xS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFHTNZFKSzVyPUK4MlI6PTZizszN NWHEVVlmW0GQR1XS
ETK-1 M{jHcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFP2[ZZKSzVyPUK4MlM1PDZizszN MkDiV2FPT0WU
LNCaP-Clone-FGC M12yTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4Xh[GlEPTB;MkmuPVI5OSEQvF2= NG\XN4ZUSU6JRWK=
SIG-M5 MonRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4PkR2lEPTB;M{CuO|k2OiEQvF2= NHjEZY9USU6JRWK=
NB6 NF;zWFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYDXeZl7UUN3ME2zNE46PTB|IN88US=> NWjU[Io3W0GQR1XS
NCI-H2107 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVHJR|UxRTNzLkKzN|gh|ryP M2nSXHNCVkeHUh?=
SNU-C1 NHvxXWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH7EXoJKSzVyPUOxMlMyOjZizszN M1TYTXNCVkeHUh?=
JAR NVrhZmF1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1;RbmlEPTB;M{GuN|c6QSEQvF2= MlT5V2FPT0WU
L-363 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWLnSnIzUUN3ME2zNk4zOTR2IN88US=> NFTQe49USU6JRWK=
EW-24 NV\URnVDT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MofPTWM2OD1|Mj6zOFc1KM7:TR?= NXHDRVE2W0GQR1XS
NB69 NIrNfGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYDISpJ3UUN3ME2zN{43PDV2IN88US=> M4GzVnNCVkeHUh?=
EW-13 MlP4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnizTWM2OD1|Mz64PVY6KM7:TR?= MWjTRW5ITVJ?
Ramos-2G6-4C10 NEHZXIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MX7JR|UxRTN2LkK5PVMh|ryP MknvV2FPT0WU
TE-11 NYrKWJR[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXPkNlN{UUN3ME2zOE41QDJ{IN88US=> NH\qUZJUSU6JRWK=
L-428 Mly5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2T6dGlEPTB;M{SuO|U{PiEQvF2= NFG0NmlUSU6JRWK=
KP-N-YN MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVnLbmR[UUN3ME2zOE46ODV5IN88US=> MV7TRW5ITVJ?
CGTH-W-1 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2jmb2lEPTB;M{[uPVA1QCEQvF2= MWLTRW5ITVJ?
K-562 M{Gw[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVzJR|UxRTN5LkC4OlQh|ryP NFPrV21USU6JRWK=
NCI-H1299 NWj5dWVoT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MknDTWM2OD1|OD6xOlA{KM7:TR?= MX\TRW5ITVJ?
RCC10RGB M3q4Rmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHW3d|FKSzVyPUO4MlIxQDNizszN M2jienNCVkeHUh?=
NCI-SNU-16 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVLJR|UxRTN6LkW2OVMh|ryP NXniW3Y6W0GQR1XS
LC-2-ad MmfXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1GyeGlEPTB;M{muOFM{PyEQvF2= MXzTRW5ITVJ?
MHH-PREB-1 Mn\tS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkPwTWM2OD1|OT63N|g5KM7:TR?= NUK1PJBvW0GQR1XS
NCI-H64 M17zZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvEbnhKSzVyPUSwMlA6PDhizszN NGCyem1USU6JRWK=
LB996-RCC MofCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmC5TWM2OD12MD64O|E3KM7:TR?= MYfTRW5ITVJ?
DEL MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVvJR|UxRTRzLkS0NFUh|ryP Ml7KV2FPT0WU
MLMA NHX3XFFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWDhelJHUUN3ME20NU44PTl3IN88US=> MWLTRW5ITVJ?
SBC-1 MlftS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn7RTWM2OD12Mj6xPFA3KM7:TR?= NEDQR2NUSU6JRWK=
MPP-89 MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{LzfGlEPTB;NEKuOVg4PSEQvF2= MULTRW5ITVJ?
MV-4-11 NYrOVIo5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkjETWM2OD12Mj65NFY4KM7:TR?= MmLOV2FPT0WU
EoL-1- MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYXWfoNsUUN3ME20OE4yPTZ6IN88US=> NUfDfXE5W0GQR1XS
CW-2 NIjqXYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTR2LkizOFIh|ryP M{jiTnNCVkeHUh?=
HT NULqWnFOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlzHTWM2OD12NT63NFA4KM7:TR?= NX65VlV2W0GQR1XS
SW954 M171bmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTR5LkSxNlgh|ryP NFftdnRUSU6JRWK=
A3-KAW M123PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXTRXmNoUUN3ME20PU45ODZzIN88US=> NXHqbm53W0GQR1XS
TC-YIK M2f5Tmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELVPY1KSzVyPUWwMlA{PjNizszN NYnwO3FtW0GQR1XS
SW962 NV74b3ZRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NF\HbWpKSzVyPUW0Mlg{PTdizszN MmfkV2FPT0WU
KP-N-RT-BM-1 M1rTfGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHvxUpZKSzVyPUW2MlY3OzhizszN Ml7DV2FPT0WU
NCI-H1395 MVrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MW\JR|UxRTV6LkixO|Ih|ryP M2PBTXNCVkeHUh?=
RPMI-8402 NGjYcmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEDVXVdKSzVyPUW4Mlk2OjZizszN NYTCcFdMW0GQR1XS
SCH NUHtbWFJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\Le2lEPTB;NkCuPVY{QCEQvF2= MnXCV2FPT0WU
NCI-H2196 NF3EeINIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{fKOWlEPTB;NkGuNlMyKM7:TR?= NUO2SpF[W0GQR1XS
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NCI-H1522 NWnXZppvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{PWS2lEPTB;NkmuNFA1PyEQvF2= NX3ZU3ZUW0GQR1XS
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NCI-H1694 M2q4emdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mmn1TWM2OD15MT6wN|Ih|ryP Mor4V2FPT0WU
NCI-H82 M1nzWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxRTdzLkm1NFch|ryP M2DxRXNCVkeHUh?=
SCC-15 NI\WZWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVrJR|UxRTd{LkO0JO69VQ>? M1OyNHNCVkeHUh?=
NCI-H1436 M2nlZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWS5d2F6UUN3ME23Nk44PDV4IN88US=> NVTweHJoW0GQR1XS
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NCI-H526 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX\JR|UxRTd6LkW4O|ch|ryP M3P3R3NCVkeHUh?=
NCI-H2171 NX34Nm1qT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUXJR|UxRTd7LkSxN|Yh|ryP NVTJRYg6W0GQR1XS
COLO-668 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\ic2lEPTB;OEGuOVg5PCEQvF2= M{\tRXNCVkeHUh?=
RS4-11 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHqO3o2UUN3ME24Nk4zPTB3IN88US=> MYnTRW5ITVJ?
NCI-H716 NXr0U3pMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3LPSmlEPTB;OEKuPVA4PSEQvF2= M2fwPXNCVkeHUh?=
LU-134-A NX;WW3k{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVHJR|UxRTh|LkGzOVEh|ryP MoO1V2FPT0WU
RPMI-8226 NVX0cJdLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHTEUIZKSzVyPUi0MlIyODdizszN MYXTRW5ITVJ?
KY821 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;CU|hKSzVyPUmxMlY2PTFizszN NWrr[2FXW0GQR1XS
ECC4 Mnr1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGHjPFlKSzVyPUmzMlgzPjlizszN NWjTZYZiW0GQR1XS
EW-3 MoDGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUTWdG52UUN3ME25OE46ODhzIN88US=> NFX1VGFUSU6JRWK=
NB7 M37nVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NULDdVA6UUN3ME25OU44Pzh4IN88US=> MVXTRW5ITVJ?
NCI-H720 NHvtNW9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV3JR|UxRTl6LkSwOlEh|ryP NEj0XWtUSU6JRWK=
NCI-H446 MkHHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXvJR|UxRTl7Lke1PFgh|ryP NFrKeFhUSU6JRWK=
NCI-H889 NXXK[2JZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2DN[2lEPTB;MUC0MlI1OiEQvF2= NY\EeFhPW0GQR1XS
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BV-173 M33rS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2fmOGlEPTB;MUC4MlczQCEQvF2= NFHMNpNUSU6JRWK=
WSU-NHL M{HLWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWTJR|UxRTFyOT62O|Eh|ryP MlvHV2FPT0WU
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DMS-79 NVy1[mZ5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXfJR|UxRTFzNz6zPFIh|ryP MVnTRW5ITVJ?
SK-MEL-1 M{j1R2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mnz1TWM2OD1zMUiuNFA6KM7:TR?= MmraV2FPT0WU
DMS-153 M3K2[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mo\0TWM2OD1zMkGuO|Q2KM7:TR?= NYL4W4l5W0GQR1XS
NCI-H510A NVvFe4tJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1r2TmlEPTB;MUK3MlMzKM7:TR?= M33rc3NCVkeHUh?=
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NB14 M4rhN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MY\JR|UxRTF2Nz6wPFIh|ryP M1Pv[XNCVkeHUh?=
MDA-MB-134-VI M3jIemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1W1PWlEPTB;MUS4MlI3QCEQvF2= MnnpV2FPT0WU
NCI-H1770 M1fGdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUXRVmtJUUN3ME2xOVYvOjd7IN88US=> NYO1R|VIW0GQR1XS
TUR Mle3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3PYRmlEPTB;MU[3Mlg4KM7:TR?= M2XHcnNCVkeHUh?=
NCI-H1417 NVrXdndXT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGOyOIVKSzVyPUG4NE4{OzFizszN MlrlV2FPT0WU
IMR-5 MnmwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3vCVWlEPTB;MUixMlU4OSEQvF2= NVzjUHluW0GQR1XS
NCI-H226 NUjFTpZsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnG2TWM2OD1zOEiuPFY3KM7:TR?= MnfvV2FPT0WU
NCI-H187 MonYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVHMZ2JWUUN3ME2xPVAvODZ2IN88US=> MX;TRW5ITVJ?
SF539 M1HxWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVfJR|UxRTF7Mj63Nlgh|ryP MVnTRW5ITVJ?
TALL-1 M3nyOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYryWVNGUUN3ME2xPVgvOzB2IN88US=> M3zhUXNCVkeHUh?=
TE-441-T NXvkRXBtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXtTWM2OD1zOUmuO|M6KM7:TR?= M2T3VXNCVkeHUh?=
REH M3PVVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUGxZZhMUUN3ME2yN|YvPjJ4IN88US=> MoXtV2FPT0WU
MS-1 M1PHOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NETCSVlKSzVyPUKzPU4yOjFizszN MXLTRW5ITVJ?
THP-1 NVXMbGZsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIHXNY5KSzVyPUK2OE44OzhizszN NVPMTZlWW0GQR1XS
NCI-H1838 Mnr1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHrK[pBKSzVyPUK3NU41PTZizszN MXvTRW5ITVJ?
P30-OHK NF;sO5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXe2bXZKUUN3ME2yPFMvQDR5IN88US=> MnPmV2FPT0WU
C8166 NXHHT2M5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVjJR|UxRTN2NT6zN|gh|ryP MYHTRW5ITVJ?

... Click to View More Cell Line Experimental Data

In vivo Administration of MG-132 effectively rescues the expression levels and plasma membrane localization of dystrophin, β-dystroglycan, α-bdystroglycan, and α-sarcoglycan in skeletal muscle fibers from mdx mice, reduces muscle membrane damage, and ameliorates the histopathological signs of muscular dystrophy. [7] MG-132 treatment significantly reduces immobilization-induced skeletal muscle atrophy in mice, by downregulating the muscle-specific ubiquitin ligases atrogin-1/MAFbx and MuRF-1 mRNA. [8]

Protocol

Kinase Assay:

[1]

+ Expand

Measurement of inhibitory activities of MG-132 against 20S proteasome:

The reaction mixture for the 20S proteasome inhibitory assay contains 0.1 M Tris-acetate, pH 7.0, 20S proteasome, MG-132, and 25 μM substrate dissolved in dimethyl sulfoxide in a final volume of 1 mL. After incuba tion at 37 °C for 15 minutes, the reaction is stopped by the addition of 0.1 mL of 10% SDS and 0.9 mL of 0.1M Tris acetate, pH 9.0. The fluorescence of the reaction products is measured. To determine the IC50 against 20S proteasome, various concentrations of MG-132 are included in the assay mixture.
Cell Research:

[3]

+ Expand
  • Cell lines: KIM-2, HC11, and ES
  • Concentrations: Dissolved in DMSO, final concentrations ~25 μM
  • Incubation Time: 24, and 48 hours
  • Method:

    Cells are exposed to various concentrations of MG-132 for 24, and 48 hours. Supernatant and monolayer cells are harvested by centrifugation and fixed in 70% ethanol in PBS for staining with acridine orange. Equal volumes of cells and acridine orange (5 mg/mL in PBS) are mixed on a microscope slide and examined by fluorescence microscopy. For annexin V analysis, cells are harvested by centrifugation and stained with annexin V and propidium iodide. For cell cycle analysis, cells are rehydrated in PBS at room temperature for 10 minutes, followed by staining with propidium iodide (5 mg/mL). All samples are analyzed using a Coulter Epics XL flow cytometer.


    (Only for Reference)
Animal Research:

[7]

+ Expand
  • Animal Models: Male mdx (C57BL/10ScSn DMD mdx) mice
  • Formulation: Dissolved in DMSO, and diluted in PBS
  • Dosages: ~10 μg/kg/day
  • Administration: Injection
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 95 mg/mL (199.73 mM)
Ethanol 95 mg/mL (199.73 mM)
Water slightly soluble or insoluble
In vivo Add solvents individually and in order:
4% DMSO+30% PEG 300+20% propylene glycol+ddH2O
2mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 475.62
Formula

C26H41N3O5

CAS No. 133407-82-6
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
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    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
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Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

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Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

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To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID