HIV Protease

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HIV Protease Inhibitors (7)

water-soluble

Cat.No. Product Name Information Product Use Citation Customer Product Validation
S1185 Ritonavir Ritonavir is an antiretroviral (HIV) drug which inhibits a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4).
  • Blood, 2012, 119(20):4686-97
  • J Immunol, 2014, 192(8):3496-506
  • Antiviral Res, 2015, 120:140-6
S1380 Lopinavir Lopinavir is a potent HIV protease inhibitor with Ki of 1.3 pM in a cell-free assay.
  • Cell, 2012, 148(1-2):201-12
  • J Immunol, 2014, 192(8):3496-506
  • Antimicrob Agents Chemother, 2014, 58(8):4875-84
S1457 Atazanavir Sulfate Atazanavir Sulfate is a HIV protease inhibitor with Ki of 2.66 nM in a cell-free assay.
  • Reprod Toxicol, 2014, 50:122-8
S1620 Darunavir Ethanolate Darunavir Ethanolate (DRV) is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.
  • J Immunol, 2014, 192(8):3496-506
  • Drug Metab Dispos, 2015, 44(3):398-408
S1639 Amprenavir Amprenavir is a potent PXR-selective agonist, and an HIV protease inhibitor, used to treat HIV.
S2319 Limonin Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.
S4282 Nelfinavir Mesylate Nelfinavir Mesylate is a potent HIV protease inhibitor with Ki of 2 nM.

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Cat.No. Product Name Solubility (25°C)
Water DMSO Ethanol
S1185 Ritonavir <1 mg/mL 100 mg/mL 3 mg/mL
S1380 Lopinavir <1 mg/mL 126 mg/mL 126 mg/mL
S1457 Atazanavir Sulfate <1 mg/mL 104 mg/mL <1 mg/mL
S1620 Darunavir Ethanolate <1 mg/mL 100 mg/mL <1 mg/mL
S1639 Amprenavir <1 mg/mL 16 mg/mL 100 mg/mL
S2319 Limonin <1 mg/mL 44 mg/mL <1 mg/mL
S4282 Nelfinavir Mesylate <1 mg/mL 100 mg/mL 100 mg/mL
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