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Lopinavir (ABT-378) Chemical Structure
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Biological Activity
Lopinavir (ABT-378) is an antiretroviral of the protease inhibitor class. As a component of combination therapy to treat HIV/AIDS. Inhibition of HIV-1 protease prevents cleavage of the viral polyprotein precursor and results in the release of immature, noninfectious virions. [1]
Chemical Information
| Molecular Weight (WM): | 628.8 |
|---|---|
| Formula: | C37H48N4O5 |
| CAS No.: | 192725-17-0 |
| Synonyms: |
ABT-378
|
| Dissolve in (25°C): | DMSO ≥126mg/mL |
| Water <1mg/mL | |
| Ethanol ≥126mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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