Research Area
Product Type
United States ( Change Country )
Ritonavir Chemical Structure
Recommended Products
Lopinavir (ABT-378)
Lopinavir is an inhibitor of the HIV protease.
Bortezomib (Velcade)
Bortezomib also known as Velcade, MG-341, PS-341 is proteasome Inhibitor, effectively inhibits proteasome activity (Ki-0.6 nM).
Danoprevir
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with an IC50 of 0.2-3.5 nM.
Glimepiride
Glimepiride is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.
Lopinavir (ABT-378)
Lopinavir is an inhibitor of the HIV protease.
Atazanavir
Atazanavir is an antiretroviral drug of the protease inhibitor (PI) class.
BMS-790052
BMS-790052 is a first-in-class, highly selective inhibitor of hepatitis C virus (HCV) NS5A with an EC50 of 9–50 pM.
VX-222
VX-222 (VCH-222) is a novel, potent and selective inhibitor of non-nucleoside polymerase of the hepatitis C virus (HCV) RNA-dependent RNA polymerase, with an IC50 range of 0.94-1.2 μM.
Telaprevir (VX-950)
Telaprevir is an investigational oral hepatitis C virus (HCV) protease inhibitor with an IC50 of < 0.2 μM
Biological Activity
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS. It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, ritonavir is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). The drug’s molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors. This discovery has drastically reduced the adverse effects and improved the efficacy of PI’s and HAART. [1]
Chemical Information
| Molecular Weight (WM): | 720.94 |
|---|---|
| Formula: | C37H48N6O5S2 |
| CAS No.: | 155213-67-5 |
| Synonyms: |
Norvir, Norvir Softgel
|
| Dissolve in (25°C): | DMSO ≥144mg/mL |
| Water <1mg/mL | |
| Ethanol ≥20mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
Research Area
Related Inhibitors
Recommended Screening Libraries
Chemical Library
A collection of 864 bioactive compounds
Inhibitor Library
A collection of 481 inhibitors
Kinase Inhibitor Library
A collection of 194 kinase inhibitors
Tyrosine Kinase Inhibitor Library
A collection of 85 tyrosine kinase inhibitors.
FDA Approved Drug Library
A collection of 426 FDA approved drugs
Natural Product Library
A collection of 139 natural products
Chemotherapeutic Agent Library
A collection of 40 chemotherapeutic agents
Epigenetics Compound library
A unique collection of 17 small molecule modulators
Stem Cell Compound library
A unique collection of 47 small molecule inhibitors
GPCR Compound library
A unique collection of 63 GPCR small molecules
Keywords:buy Ritonavir | Ritonavir supplier | purchase Ritonavir | Ritonavir cost | Ritonavir manufacturer | order Ritonavir | Ritonavir distributor