P2 Receptor

Signaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1258 Prasugrel <1 mg/mL 30 mg/mL 7 mg/mL
S1415 Clopidogrel 78 mg/mL 83 mg/mL 46 mg/mL
S2855 MRS 2578 <1 mg/mL 42 mg/mL <1 mg/mL
S4079 Ticagrelor <1 mg/mL 100 mg/mL 53 mg/mL
S1984 Ticlopidine HCl 4 mg/mL 1 mg/mL 1 mg/mL
S8519 A-317491 <1 mg/mL 100 mg/mL 100 mg/mL
S7705 A-438079 HCl 61 mg/mL 61 mg/mL 20 mg/mL
S4637 Prasugrel Hydrochloride <1 mg/mL 46 mg/mL 9 mg/mL

Isoform-specific Inhibitors

Catalog No. Information Product Use Citations Product Validations
S1258

Prasugrel

Prasugrel is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.

S1415

Clopidogrel

Clopidogrel is an oral, thienopyridine class antiplatelet agent.

S2855

MRS 2578

MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.

S4079

Ticagrelor

Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM.

S1984

Ticlopidine HCl

Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.

S8519New

A-317491

A-317491 is a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors with Ki values of 22 nM and 9 nM for human P2X3 and P2X2/3 receptors.

S7705

A-438079 HCl

A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.

S4637

Prasugrel Hydrochloride

Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.