Catalog No.S1415

Clopidogrel is an oral, thienopyridine class antiplatelet agent.

Price Stock Quantity  
USD 70 In stock
USD 170 In stock
Bulk Inquiry

Massive Discount Available

Free Overnight Delivery on all orders over $ 500.

Clopidogrel Chemical Structure

Clopidogrel Chemical Structure
Molecular Weight: 419.9

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Clopidogrel is available in the following compound libraries:

Product Information

  • Compare P2 Receptor Inhibitors
    Compare P2 Receptor Products
  • Research Area

Product Description

Biological Activity

Description Clopidogrel is an oral, thienopyridine class antiplatelet agent.
Targets P2Y12 [1]
In vitro Clopidogrel is converted to its active metabolite by cytochrome P450 (CYP) enzymes. [1] Clopidogrel (1 μM) also inhibits EGF-stimulated EGF receptor, PERK expression, and cell proliferation in RGM-1 cells (P<0.05), and causes much less inhibition of EGF-stimulated cell proliferation in EGF receptor over-expressed RGM-1 cells than in RGM-1 cells (22% vs. 32% reduction). [2] Clopidogrel increases blood vessel number, reduces polymorphonuclear count and decreases attachment and bone loss, also decreases osteoclast number in rats submitted or not to periodontal repair. Clopidogrel decreases CXCL4, CXCL12 and PDGF content compared with saline-treated rats, without affecting CXCL5. [3]
In vivo Clopidogrel (2mg and 10mg/kg/day) significantly decreases ulcer-induced gastric epithelial cell proliferation and ulcer-stimulated expressions of EGF receptor and phosphorylated extracellular signal-regulated kinase (PERK) at the ulcer margin of rats. [2] Clopidogrel improves endothelial function and NO bioavailability in rats with congestive heart failure. Clopidogrel-treated Congestive heart failure (CHF) rat displays enhances phosphorylation of AKT and eNOS. [4] The clopidogrel/aspirin combination shows only additive-type effects on bleeding time prolongation induced by ear transection in the rabbit, therefore showing that combined inhibition of cyclooxygenase and ADP's effects provide a marked enhanced antithrombotic efficacy. [5]

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDog
Weight (kg)
Body Surface Area (m2)0.0070.0250.
Km factor36128520
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)


[1] Laine L, et al. Am J Gastroenterol, 2010, 105(1), 34-41.

[2] Luo JC, et al. Eur J Pharmacol, 2012, 695(1-3), 112-119.

view more

Clinical Trial Information( data from, updated on 2016-07-30)

NCT Number Recruitment Conditions Sponsor
Start Date Phases
NCT02777580 Not yet recruiting Myocardial Infarction Katholieke Universiteit Leuven|Boehringer Ingelheim|Life  ...more Katholieke Universiteit Leuven|Boehringer Ingelheim|Life Sciences Research Partners|Fund for Clinical Cardiovascular Research at LRD September 2016 Phase 2
NCT02829151 Not yet recruiting Critical Limb Ischemia Yonsei University July 2016 Phase 4
NCT02831218 Not yet recruiting Percutaneous Transluminal Coronary Angioplasty CHEOL WHAN LEE, M.D., Ph.D|CardioVascular Research Founda  ...more CHEOL WHAN LEE, M.D., Ph.D|CardioVascular Research Foundation, Korea|Asan Medical Center July 2016 Phase 4
NCT02433587 Not yet recruiting Peripheral Arterial Disease|Endovascular Procedures University Hospital Case Medical Center July 2016 Phase 3
NCT02776540 Recruiting Ischemic Cerebrovascular Accident Ain Shams University May 2016 Phase 4

view more

Chemical Information

Download Clopidogrel SDF
Molecular Weight (MW) 419.9


CAS No. 120202-66-6
Storage 3 years -20℃powder
2 years -80℃in solvent
Synonyms SR-25990C
Solubility (25°C) * In vitro DMSO 83 mg/mL (197.66 mM)
Water 78 mg/mL (185.75 mM)
Ethanol 46 mg/mL (109.54 mM)
In vivo
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Related P2 Receptor Products

  • A-438079 HCl

    A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.

  • AZD3839

    AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.

  • Xanthohumol

    Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Phase 1.

  • Prasugrel

    Prasugrel is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.

  • Ticlopidine HCl

    Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.

  • MRS 2578

    MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.

  • Ticagrelor

    Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM.

    Features:First-in-class of a new type of P2Y12 antagonist known as cyclopentyl-triazolo-pyrimidines.


    DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.

  • RO4929097

    RO4929097 is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.

  • Celecoxib

    Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM in Sf9 cells.

Recently Viewed Items

Tags: buy Clopidogrel | Clopidogrel ic50 | Clopidogrel price | Clopidogrel cost | Clopidogrel solubility dmso | Clopidogrel purchase | Clopidogrel manufacturer | Clopidogrel research buy | Clopidogrel order | Clopidogrel mouse | Clopidogrel chemical structure | Clopidogrel mw | Clopidogrel molecular weight | Clopidogrel datasheet | Clopidogrel supplier | Clopidogrel in vitro | Clopidogrel cell line | Clopidogrel concentration | Clopidogrel nmr
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Contact Us