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Serotonin Transporter

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Cat.No. Product Name Information Product Use Citations Product Validations
S1336 Fluvoxamine (DU-23000) maleate Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.
Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
Cell Rep, 2024, 43(10):114818
Brain Res, 2024, 1838:149011
S3005 Paroxetine HCl Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.
Adv Sci (Weinh), 2025, 12(33):e01981
Cell Rep, 2024, 43(10):114818
Nat Commun, 2022, 13(1):3034
S4053 Sertraline HCl Sertraline HCl (CP-51974-1) is a 5-HT antagonist with Ki of 13 nM.
EMBO Mol Med, 2025, 17(4):625-644
Cell Rep, 2024, 43(10):114818
Antimicrob Agents Chemother, 2021, AAC.01146-20
S2084 Duloxetine HCl Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
Cancers (Basel), 2022, 14(19)4883
Drug Metab Dispos, 2015, 44(3):378-88
J Pharmacol Exp Ther, 2014, 349(3):402-7
Verified customer review of Duloxetine HCl
S1441 Venlafaxine HCl Venlafaxine HCl(Wy 453 HCl) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
Am J Cancer Res, 2024, 14(3):1087-1100
Nat Commun, 2020, 14;11(1):1825
Drug Metab Dispos, 2020, 48(10):1044-1052
S4064 Escitalopram Oxalate Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
Proc Natl Acad Sci U S A, 2025, 122(10):e2420499122
Cell Rep, 2024, 43(10):114818
J Matern Fetal Neonatal Med, 2023, 36(1):2183468
S3183 Amitriptyline HCl Amitriptyline HCl is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. This compound also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. It is a tricyclic antidepressant (TCA).
Environ Toxicol Chem, 2021, 10.1002/etc.5018
PLoS Pathog, 2020, 16;16(3):e1008341
Sci Rep, 2018, 8(1):15753
S4377 Imipramine HCl Imipramine (Melipramine,G 22355) is a tricyclic antidepressant (TCA) of the dibenzazepine group, mainly used in the treatment of major depression and enuresis (inability to control urination).
Cancer Drug Resist, 2022, 5(3):612-624
Antioxidants (Basel), 2021, 10(6)956
Biomedicines, 2021, 9(9)1230
S2541 Clomipramine HCl Clomipramine HCl is a tricyclic antidepressant acting as a potent inhibitor of 5-HT reuptake with an IC50 value of 1.5 nM. Clomipramine hydrochloride is used in research on depression, anxiety, and obsessive-compulsive disorder (OCD).
Biomed Pharmacother, 2022, 153:113328
bioRxiv, 2020, 2020/9/20.4.7.30734
S4113 Desvenlafaxine Desvenlafaxine (WY 45233 Succinate) is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.
Am J Cancer Res, 2024, 14(3):1087-1100
Drug Metab Dispos, 2020, 48(10):1044-1052