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Serotonin Transporter

Other Neuronal Signaling Related Inhibitors

Secretase GluR GABA Receptor Dopamine Receptor 5-HT Receptor P2 Receptor AChR Histamine Receptor MAO Beta Amyloid
Cat.No. Product Name Information Product Use Citations Product Validations
S1336 Fluvoxamine (DU-23000) maleate Fluvoxamine maleate (DU-23000, MK-264) is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.
mBio, January 18, 2022, e0337721
eLife, February 09, 2026, e103016
Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
S3005 Paroxetine HCl Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.
Molecular Therapy Oncology, December 09 2025, 201109
American Journal of Cancer Research, April 15 2022, 1465-1483
Adv Sci (Weinh), 2025, 12(33):e01981
S4064 Escitalopram Oxalate Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
eLife, February 9, 2026, RP103016
Molecular Cancer Therapeutics, December 2, 2022, 1810-1822
eLife, 2026, e103016
S4053 Sertraline HCl Sertraline HCl (CP-51974-1) is a 5-HT antagonist with Ki of 13 nM.
EMBO Mol Med, 2025, 17(4):625-644
Cell Rep, 2024, 43(10):114818
Antimicrob Agents Chemother, 2021, AAC.01146-20
S2541 Clomipramine HCl Clomipramine HCl is a tricyclic antidepressant acting as a potent inhibitor of 5-HT reuptake with an IC50 value of 1.5 nM. Clomipramine hydrochloride is used in research on depression, anxiety, and obsessive-compulsive disorder (OCD).
Infectious Medicine, 2024, 100130
Biomed Pharmacother, 2022, 153:113328
Pharmaceuticals, 2022, 241
S2084 Duloxetine HCl Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
Autophagy, 2026, 1-27.
Cancers (Basel), 2022, 14(19)4883
Drug Metab Dispos, 2015, 44(3):378-88
Verified customer review of Duloxetine HCl
S1441 Venlafaxine HCl Venlafaxine HCl(Wy 453 HCl) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
Am J Cancer Res, 2024, 14(3):1087-1100
bioRxiv, 2023, 2023.07.12.548707
Nat Commun, 2020, 14;11(1):1825
S3183 Amitriptyline HCl Amitriptyline HCl is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. This compound also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. It is a tricyclic antidepressant (TCA).
Proceedings of the National Academy of Sciences, 2021, e2026403118
Environ Toxicol Chem, 2021, 10.1002/etc.5018
PLoS Pathog, 2020, 16;16(3):e1008341
S5947 Amitriptyline Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. This compound is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. It also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
Cancer Cell, 2025, 43(4):776-796.e14
Cancer Cell, 2025, 776-796.e14
Proceedings of the National Academy of Sciences, 2021, e2026403118
S4377 Imipramine HCl Imipramine (Melipramine,G 22355) is a tricyclic antidepressant (TCA) of the dibenzazepine group, mainly used in the treatment of major depression and enuresis (inability to control urination).
Cancer Drug Resist, 2022, 5(3):612-624
Antioxidants (Basel), 2021, 10(6)956
Biomedicines, 2021, 9(9)1230