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5-HT Receptor

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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S1333 Fluoxetine HCl Fluoxetine HCl is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
Cell Rep, 2024, 43(10):114818
Int Immunopharmacol, 2024, 128:111524
Front Psychiatry, 2023, 14:1198502
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S2493 Olanzapine Olanzapine (LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.
Brain Behav Immun, 2025, 130:106111
Mol Psychiatry, 2025, 10.1038/s41380-025-03374-6
FASEB J, 2025, 39(3):e70355
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S1975 Aripiprazole Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.
Mol Psychiatry, 2025, 10.1038/s41380-025-03374-6
Biomol Ther (Seoul), 2025, 33(1):170-181
J Dev Biol, 2025, 13(3)22
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S2459 Clozapine Clozapine (HF 1854, LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia.
Clin Exp Metastasis, 2025, 42(2):12
J Immunother Cancer, 2024, 12(11)e009805
Alzheimers Dement, 2023, 10.1002/alz.13090
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S2663 WAY-100635 Maleate WAY-100635 Maleate is a potent and selective 5-HT receptor antagonist with IC50 of 0.95 nM.
Nat Neurosci, 2025, 28(11):2285-2295
Gastroenterology, 2024, 167(5):993-1007
Med Sci Sports Exerc, 2022, 54(4):566-581
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S2346 Puerarin Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.
Acta Biochim Biophys Sin (Shanghai), 2024, 56(2):270-279
Int J Mol Sci, 2023, 24(9)8328
Ecotoxicol Environ Saf, 2022, 247:114239
S4244 Serotonin (5-HT) HCl Serotonin (5-HT) HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.
EMBO Mol Med, 2025, 10.1038/s44321-025-00293-5
Anim Biosci, 2025, 38(8):1633-1643
Mod Pathol, 2022, 10.1038/s41379-022-01110-x
S4749 Citalopram HBr Citalopram HBr (Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr), an antidepressant, is an orally administered selective serotonin reuptake inhibitor (SSRI) with IC50 of 1.8 nM.
Cell Rep, 2024, 43(10):114818
Chem Biol Interact, 2024, 403:111246
Aging (Albany NY), 2021, 13(11):14729-14744
S1283 Asenapine maleate Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.
J Adv Res, 2024, S2090-1232(24)00079-1
Cell Commun Signal, 2024, 22(1):266
Mol Cancer, 2023, 22(1):136
S1444 Ziprasidone HCl Ziprasidone HCl (CP-88059) is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.
UNIVERSITY OF PÉCS, 2023,
Anticancer Res, 2021, 41(2):687-697
Molecules, 2020, 25(18)E4206
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