Home Neuronal Signaling 5-HT Receptor

5-HT Receptor Modulators

Cat.No. Product Name Information Product Use Citations Product Validations
S3716 Flibanserin Flibanserin (BIMT-17, BIMT-17-BS) is a nonhormonal, centrally acting molecule that acts as an agonist at postsynaptic 5-HT1A receptors and as an antagonist at 5-HT2A receptors.
Arch Biochem Biophys, 2024, 754:109958
Nat Commun, 2021, 12(1):5919
S5858 Vilazodone Vilazodone (EMD-68843, SB-659746A) is a novel antidepressant having a selective serotonin (5-HT) reuptake inhibitory and 5-HT1A receptor partial agonist activity. The affinity of vilazodone is much higher in the 5-HT reuptake site (Ki=0.1 nM) than in norepinephrine (Ki=56 nM) and dopamine (Ki=37 nM) sites.
J Pain, 2019, 20(1):16.e1-16.e16
S5843 Cinitapride Hydrogen Tartrate Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
S5949 Metoclopramide hydrochloride hydrate Metoclopramide hydrochloride (Clorpa, Gimoti, Maxolon, Reglan) hydrate is primarily a Dopamine receptor antagonist, with 5HT3 receptor antagonist and 5HT4 receptor agonist activity, and used as an antiemetic and gastroprokinetic.
Anticancer Drugs, 2022, 10.1097/CAD.0000000000001344
Pharmazie, 2021, 76(4):172-174