Catalog No.S4686 Synonyms: Alpha-Tocopherol, D-alpha-Tocopherol, 5,7,8-Trimethyltocol|(+)-alpha-Tocopherol
Molecular Weight(MW): 430.71
Vitamin E is a fat-soluble vitamin with potent antioxidant properties. It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription.
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|Description||Vitamin E is a fat-soluble vitamin with potent antioxidant properties. It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription.|
vitamin E is capable of inducing necrosis in TC-1 cells and has antioxidant effects against nitric oxide.
|In vivo||Vitamin E induces TC-1 cell necrosis in vivo and reduces tumor volume in TC-1 tumor-bearing mice. Vitamin E reduces myeloid derived suppressor cells(MDSCs) in tumors of TC-1 tumor-bearing mice and enhances T cell accumulation.|
|Synonyms||Alpha-Tocopherol, D-alpha-Tocopherol, 5,7,8-Trimethyltocol|(+)-alpha-Tocopherol|
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT03613389||Enrolling by invitation||Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy||Cairo University|National Cancer Institute (NCI)||January 1 2019||Not Applicable|
|NCT03669133||Recruiting||NAFLD|NASH - Nonalcoholic Steatohepatitis|HIV Infections||Indiana University School of Medicine|Indiana University||December 31 2018||Phase 2|
|NCT03416777||Not yet recruiting||Nutrition Aspect of Cancer|Diet Modification|Cancer of Colon||Azienda Ospedaliero-Universitaria Careggi||October 1 2018||Not Applicable|
|NCT03668964||Enrolling by invitation||Healthy Volunteers||DSM Nutritional Products Inc.|Atlantia Food Clinical Trials||August 20 2018||Not Applicable|
|NCT03557229||Recruiting||Oxidative Stress|Septic Shock||American British Cowdray Medical Center||July 23 2018||Phase 3|
|NCT03674385||Recruiting||Clomiphene Citrate Resistant Polycystic Ovary Syndrome||Ain Shams University|Misr University for Science and Technology||July 19 2018||Phase 2|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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