CAS No. 53-84-9

Batch: Purity:99.99
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NAD+ (β-DPN) Chemical Structure
Chemical Structure
Check the NAD+ (β-DPN) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
CAS Number 53-84-9
Molecular Formula

C21H27N7O14P2
Molecular Weight (MW) 663.43
SMILES C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
InChIKey BAWFJGJZGIEFAR-NNYOXOHSSA-N

Ordering Information

Biological Activity

NAD+ (β-Nicotinamide Adenine Dinucleotide) is an essential metabolic coenzyme and key electron carrier that functions as a critical substrate for NAD+-dependent enzymes, including sirtuins and poly(ADP-ribose) polymerases (PARPs). By shuttling electrons in oxidation-reduction reactions, it maintains mitochondrial bioenergetics and cellular redox state. Fluctuations in cellular NAD+ levels regulate diverse physiological pathways involved in oxidative phosphorylation, DNA repair, nutrient sensing, and metabolic homeostasis. [1][2]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 50 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.