DFO

Catalog No.S6849 Synonyms: 9H-1,8-Diazafluoren-9-one, 1,8-Diazafluoren-9-one

For research use only.

DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids present in the papillary exudate.

DFO Chemical Structure

CAS No. 54078-29-4

Selleck's DFO has been cited by 2 Publications

Purity & Quality Control

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Biological Activity

Description DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids present in the papillary exudate.
Targets
amino acids [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 182.18
Formula

C11H6N2O

CAS No. 54078-29-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC2=C(C(=O)C3=C2C=CC=N3)N=C1

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05259709 Not yet recruiting Drug: 89Zr˗DFO˗REGN5054|Drug: cemiplimab Advanced Solid Tumor|Metastatic Solid Tumor Regeneron Pharmaceuticals June 23 2022 Phase 1
NCT04566991 Recruiting Drug: Deferoxamine|Drug: Placebo Aneurysmal Subarachnoid Hemorrhage Aditya S. Pandey MD|Michigan Medicine PKUHSC Joint Institute for Translational & Clinical Research|University of Michigan March 20 2022 Phase 2
NCT04706715 Recruiting Other: 89Zr-DFO-REGN3767|Drug: Cemiplimab Metastatic Solid Tumor University Medical Center Groningen|Regeneron Pharmaceuticals January 18 2022 Phase 1|Phase 2
NCT05184816 Recruiting Drug: Deferoxamine (DFO) Leptomeningeal Metastases Memorial Sloan Kettering Cancer Center|Center for Experimental Therapeutics|F.M. KIRBY FOUNDATION December 22 2021 Phase 1
NCT04863794 Active not recruiting Drug: RO7248824 Angelman Syndrome Hoffmann-La Roche April 29 2021 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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