Diltiazem HCl

For research use only.

Catalog No.S1865 Synonyms: RG 83606 HCl

2 publications

Diltiazem HCl  Chemical Structure

CAS No. 33286-22-5

Diltiazem (Tiazac, RG 83606) HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 90 In stock
USD 70 In stock
USD 210 In stock
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Selleck's Diltiazem HCl has been cited by 2 publications

1 Customer Review

  • Gentisic acid reduces interstitial and perivascular fibrosis in mice with transverse aortic constriction (TAC). Representative images of Masson's trichrome staining of the hearts of mice in the sham and TAC + vehicle, gentisic acid, bisoprolol, or diltiazem groups. Scale bar = 50 μm. A, Interstitial fibrosis and B, perivascular fibrosis are shown. Fibrotic areas are stained blue.

    J Cell Mol Med, 2018, 22(12):5964-5977. Diltiazem HCl purchased from Selleck.

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Biological Activity

Description Diltiazem (Tiazac, RG 83606) HCl is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.
Targets
Calcium channel [1]

Protocol

Solubility (25°C)

In vitro DMSO 90 mg/mL (199.56 mM)
Water 90 mg/mL (199.56 mM)
Ethanol ''4 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 450.98
Formula

C22H26N2O4S.HCl

CAS No. 33286-22-5
Storage powder
in solvent
Synonyms RG 83606 HCl
Smiles CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID