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Endogenous Metabolite inhibitors

Other Metabolism Related Inhibitors

Dehydrogenase Transferase DPP Aminopeptidase Procollagen C Proteinase P450 (e.g. CYP17) Phospholipase (e.g. PLA) Factor Xa PDE DHFR
Cat.No. Product Name Information Product Use Citations Product Validations
S5259 β-nicotinamide mononucleotide (NMN) Nicotinamide mononucleotide (β-NM, NMN), one of the key precursors of NAD+ and products of the NAMPT reaction , is converted to NAD+ by nicotinamide mononucleotide adenylyltransferase.
Nat Commun, 2025, 16(1):212
MedComm (2020), 2025, 6(3):e70075
PLoS Pathog, 2025, 21(5):e1013163
S5992 Heparan Sulfate Heparan sulfate (HS, Heparitin sulfate, Alpha-idosane, HHS 5, N-Acetylheparan Sulfate, Suleparoid, Tavidan), a constituent of HS proteoglycans (HSPGs), is a linear polysaccharide present on the cell surface. Heparan sulfate influences the binding affinity of intestinal epithelium cells (IECs) to Wnt, thereby promoting activation of canonical Wnt signaling and facilitating regeneration of small intestinal crypts after epithelial injury.
Mol Ther Methods Clin Dev, 2025, 33(1):101426
iScience, 2024, 27(6):110120
bioRxiv, 2024, 2024.05.23.595417
S9793 4-HNE (4-Hydroxynonenal) 4-HNE (4-Hydroxynonenal) is one of the major end products of lipid peroxidation and has been widely accepted as an inducer of oxidative stress.
Nat Commun, 2022, 13(1):5545
S5109 Ademetionine (S-Adenosylmethionine) Ademetionine (AdoMet, S-Adenosylmethionine, SAMe), also known as SAMe, is a specific form of the amino acid methionine known as S-adenosyl-methionine. It is essential for the formation of glutathione, a water-soluble peptide that helps the body fight free radicals.
Pharmaceuticals (Basel), 2025, 18(9)1395
J Oral Microbiol, 2024, 16(1):2292375
Nat Metab, 2023, 10.1038/s42255-023-00861-4
S6010 Sodium L-lactate Sodium L-lactate is used as a food additive, preservative, acidity regulator and bulking agent.
Cell Commun Signal, 2025, 23(1):104
J Transl Med, 2025, 23(1):69
EMBO Rep, 2024, 25(12):5599-5619
S1466 Calcitriol (1,25-Dihydroxyvitamin D3) Calcitriol is a nonselective vitamin D receptor activator/agonist(VDRA), exhibiting a 10-fold higher vitamin D receptor (VDR) binding affinity(IC50=0.4 nM) than the selective VDRA paricalcitol. Solutions are unstable and should be fresh-prepared.
Cell Commun Signal, 2025, 23(1):104
Cancer Sci, 2025, 116(7):1871-1882
Cancer Sci, 2025, 116(7):1871-1882
Verified customer review of Calcitriol (1,25-Dihydroxyvitamin D3)
S2298 Fisetin Fisetin (Fustel) is a potent sirtuin activating compound (STAC) and an agent that modulates sirtuins.
Sci Adv, 2025, 11(17):eads1875
Mol Cancer, 2024, 23(1):222
Cell Death Dis, 2024, 15(8):608
Verified customer review of Fisetin
S5726 Liothyronine (Triiodothyronine, T3) T3 (Triiodothyronine) is a thyroid hormone that affects various physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.This product is soluble but easy to precipitate after freezing in DMSO. 0.1 M NaOH is recommended as a stock solution.
STAR Protoc, 2025, 6(2):103834
Cancers (Basel), 2024, 16(23)4069
Invest Ophthalmol Vis Sci, 2024, 65(4):43
S5324 6-OHDA (Oxidopamine hydrobromide) 6-OHDA (Oxidopamine hydrobromide) is a neurotoxic synthetic organic compound that acts as an antagonist of the neurotransmitter dopamine with potential antineoplastic activity. 6-OHDA (Oxidopamine hydrobromide) can be used to induce animal models of Parkinson's Disease.Solutions are unstable and should be fresh-prepared.
PLoS One, 2024, 19(12):e0316179
Ther Adv Chronic Dis, 2021, 12:2040622321998139