Mupirocin

Catalog No.S4297

Mupirocin is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections.

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Mupirocin Chemical Structure

Mupirocin Chemical Structure
Molecular Weight: 500.62

Validation & Quality Control

Quality Control & MSDS

Product Information

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Product Description

Biological Activity

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDog
Weight (kg)0.020.151.80.40.0810
Body Surface Area (m2)0.0070.0250.150.050.020.5
Km factor36128520
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)

Clinical Trial Information( data from http://clinicaltrials.gov, updated on 2016-06-25)

NCT Number Recruitment Conditions Sponsor
/Collaborators
Start Date Phases
NCT02547103 Not yet recruiting End Stage Renal Disease|Peritoneal Dialysis Chiang Mai University|Health Systems Research Institute,  ...more Chiang Mai University|Health Systems Research Institute, Thailand November 2015 Phase 4
NCT02619773 Enrolling by invitation Surgical Site Infections Gundersen Lutheran Medical Foundation|Gundersen Lutheran  ...more Gundersen Lutheran Medical Foundation|Gundersen Lutheran Health System November 2015 --
NCT02566928 Recruiting Methicillin-Resistant Staphylococcus Aureus|Recurrence|Staphylococcal Skin Infections|Antibiotic Resistance Clinical Directors Network|Rockefeller University|Patient  ...more Clinical Directors Network|Rockefeller University|Patient-Centered Outcomes Research Institute October 2015 --
NCT02572791 Recruiting Skin and Subcutaneous Tissue Bacterial Infections|Staphylococcus Aureus|MRSA - Methicillin Resistant Staphylococcus Aureus Infection Washington University School of Medicine October 2015 Phase 4
NCT02560155 Recruiting Orthopedic Disorders|Surgical Site Infection Lindenhof AG|Clinical Trials Unit Bern (CTU)|Lindenhofsti  ...more Lindenhof AG|Clinical Trials Unit Bern (CTU)|Lindenhofstiftung|Labormedizinisches Zentrum Dr. Risch October 2015 --

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Chemical Information

Download Mupirocin SDF
Molecular Weight (MW) 500.62
Formula

C26H44O9

CAS No. 12650-69-0
Storage 3 years -20℃powder
6 months-80℃in solvent
Synonyms N/A
Solubility (25°C) * In vitro DMSO 100 mg/mL warming (199.75 mM)
Ethanol 100 mg/mL (199.75 mM)
Water 46 mg/mL warming (91.88 mM)
In vivo
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name (2E)-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid-8-carboxyoctyl ester

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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