Mupirocin

Catalog No.S4297

Mupirocin Chemical Structure

Molecular Weight(MW): 500.62

Mupirocin is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections.

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Notes:

2. For more details, such as half maximal inhibitory concentrations (IC50s) and working concentrations of each inhibitor, please click on the link of the inhibitor of interest.
3. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
4. Orange "√" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

Biological Activity

Description Mupirocin is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections.
Targets
isoleucyl t-RNA synthetase [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 100 mg/mL warmed (199.75 mM)
Ethanol 100 mg/mL (199.75 mM)
Water 46 mg/mL warmed (91.88 mM)
In vivo

* 1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 500.62
Formula

C26H44O9

CAS No. 12650-69-0
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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    C2
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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

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Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02963129 Not yet recruiting Hereditary Hemorrhagic Telangiectasia|Epistaxis Hospital Italiano de Buenos Aires June 2017 Phase 3
NCT02967432 Recruiting Staphylococcus Crouse Hospital|Jana Shaw, MD|Steven Gross, MD|David Martin, RN|Dale Franz, RPh|Rachel Carey October 2016 Phase 2
NCT02547103 Recruiting End Stage Renal Disease|Peritoneal Dialysis Chiang Mai University|Health Systems Research Institute, Thailand May 2016 Phase 4
NCT02619773 Enrolling by invitation Surgical Site Infections Gundersen Lutheran Medical Foundation|Gundersen Lutheran Health System November 2015 --
NCT02560155 Recruiting Orthopedic Disorders|Surgical Site Infection Lindenhof AG|Clinical Trials Unit Bern (CTU)|Lindenhofstiftung|Labormedizinisches Zentrum Dr. Risch October 2015 --
NCT02566928 Recruiting Methicillin-Resistant Staphylococcus Aureus|Recurrence|Staphylococcal Skin Infections|Antibiotic Resistance Clinical Directors Network|Rockefeller University|Patient-Centered Outcomes Research Institute October 2015 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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DNA/RNA Synthesis Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID