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Bis(2-ethylhexyl) phthalate

Name: Bis(2-ethylhexyl) phthalate
Brand: Selleck Chemicals
SKU: S3360
Rating: 5 (1 reviews)

Synonyms: Dioctyl phthalate, DOP, Diplast O, ESBO-D 82, Ergoplast FDO, Ergoplast FDO-S, Etalon

Catalog No.S3360 Purity: 99.87%

Bis(2-ethylhexyl) phthalate (Dioctyl phthalate, DOP, Diplast O, ESBO-D 82, Ergoplast FDO, Ergoplast FDO-S, Etalon) induces DNA strand breaks and gene expression alterations in larval zebrafish Danio rerio.

Bis(2-ethylhexyl) phthalate Chemical Structure

CAS: 117-81-7

Purity & Quality Control

Batch: S336001 Purity: 99.87%

99.87

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Signaling Pathway

DNA/RNA Synthesis Signaling Pathway

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description	Bis(2-ethylhexyl) phthalate (Dioctyl phthalate, DOP, Diplast O, ESBO-D 82, Ergoplast FDO, Ergoplast FDO-S, Etalon) induces DNA strand breaks and gene expression alterations in larval zebrafish Danio rerio.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT03446807	Withdrawn	Parkinson Disease\|Multiple System Atrophy\|Progressive Supranuclear Palsy	Loma Linda University\|H. Lundbeck A/S	December 2021	Phase 2
NCT04977388	Recruiting	Menkes Disease\|Occipital Horn Syndrome	Stephen G. Kaler MD\|Nationwide Children''s Hospital	July 12 2021	Phase 1\|Phase 2
NCT04922203	Enrolling by invitation	in Situ Simulation	Jean François Brichant\|University of Liege	May 28 2021	Not Applicable
NCT04682236	Unknown status	Acute Renal Failure	University Hospital Strasbourg France	November 25 2020	--

References

[1] Halis Boran, Serap Terzi. Toxicol Ind Health. 2019 Aug;35(8):520-529.

Chemical Information & Solubility

Molecular Weight	390.56	Formula	C₂₄H₃₈O₄
CAS No.	117-81-7	SDF	--
Density	0.985 g/mL
Smiles	CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC
Storage (From the date of receipt)	2 years 4°C liquid	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	2 years 4°C liquid		1 month-20°Cin solvent

In vitro
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In vivo
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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

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% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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