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Riluzole (Rilutek)

Riluzole(Rilutek) is a drug used to treat amyotrophic lateral sclerosis.

Catalog No.S1614

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50mg

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Riluzole (Rilutek) Chemical Structure
Molecular Weight: 234.2

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Riluzole (Rilutek) is available in the following compound libraries:

FDA Approved Drug Library (96-well) Chemical Library (96-well)

Product Information

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Research Area
Research Area
Dr. Antonino Maria Sparta demonstrates a breakthrough in leukemia research by utilizing two inhibitors produced by Selleck Chemicals.

Cat.No.	Product Name	Solubility (25°C)
S1614	Riluzole (Rilutek)	<1 mg/mL	47 mg/mL	47 mg/mL
S1693	Carbamazepine (Carbatrol)	<1 mg/mL	47 mg/mL	18 mg/mL
S2524	Phenytoin sodium (Dilantin)	3 mg/mL	32 mg/mL	11 mg/mL
S2785	A-803467	<1 mg/mL	72 mg/mL	11 mg/mL
S3024	Lamotrigine	<1 mg/mL	10 mg/mL	3 mg/mL
S1256	Rufinamide (Banzel)	<1 mg/mL	48 mg/mL	<1 mg/mL
S1391	Oxcarbazepine	<1 mg/mL	7 mg/mL	<1 mg/mL
S2500	Propafenone (Rytmonorm) HCl	<1 mg/mL	69 mg/mL	<1 mg/mL
S2525	Phenytoin (Lepitoin)	<1 mg/mL	51 mg/mL	15 mg/mL
S2560	Amiloride HCl dihydrate	<1 mg/mL	60 mg/mL	<1 mg/mL
S1828	Proparacaine HCl	66 mg/mL	12 mg/mL	<1 mg/mL
S2110	Vinpocetine (Cavinton)	<1 mg/mL	<1 mg/mL
S2118	Ibutilide fumarate	89 mg/mL	89 mg/mL	89 mg/mL
S3064	Ambroxol HCl	<1 mg/mL	3 mg/mL	<1 mg/mL
S4016	Ouabain	<1 mg/mL	146 mg/mL	146 mg/mL
S4023	Procaine (Novocaine) HCl	55 mg/mL	55 mg/mL	<1 mg/mL
S4038	Dibucaine (Cinchocaine) HCl	76 mg/mL	76 mg/mL	76 mg/mL
S4080	Triamterene	<1 mg/mL	20 mg/mL	<1 mg/mL

Product Description

Biological Activity Chemical Information Tech Support & FAQs

Biological Activity

Riluzole(Rilutek) is a drug used to treat amyotrophic lateral sclerosis. It delays the onset of ventilator-dependence or tracheostomy in selected patients and may increase the survival approximately 3–5 months. ^[1] Its pharmacological activities in motor neurons include the following: 1) an inhibitory effect on glutamate release 2) inactivation of voltage-dependent sodium channels 3) interference with intracellular events that follow transmitter binding at excitatory amino acid receptors. In animal models, this agent has been shown to exhibit myorelaxant and sedative activities, apparently due to the blockade of glutamatergic neurotransmission. ^[1]

Chemical Information

Download Riluzole (Rilutek) SDF

Molecular Weight (MW)	234.2
Formula	C₈H₅F₃N₂OS
CAS No.	1744-22-5
Synonyms	PK-26124, RP-54274, Rilutek

Solubility (25°C) DMSO 47 mg/mL Water <1 mg/mL Ethanol 47 mg/mL
Storage	2 years -20°CPowder
	2 weeks4°Cin DMSO
	6 months-80°Cin DMSO

Chemical Name

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Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Riluzole (Rilutek)