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S1614
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Riluzole (Rilutek) |
Riluzole(Rilutek) is a drug used to treat amyotrophic lateral sclerosis. |
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S1693
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Carbamazepine (Carbatrol) |
Carbamazepine (Carbatrol) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes. |
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S2524
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Phenytoin sodium (Dilantin) |
Phenytoin sodium (Dilantin) is an inactive voltage-gated sodium channel stabilizer. |
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S2785
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A-803467 |
A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM. |
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S3024
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Lamotrigine |
Lamotrigine is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, respectively. |
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S4080
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Triamterene |
Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM. |
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S4038
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Dibucaine (Cinchocaine) HCl |
Dibucaine (Cinchocaine) HCl is a local anesthetics. |
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S4023
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Procaine (Novocaine) HCl |
Procaine (Novocaine) HCl is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM. |
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S4016
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Ouabain |
Ouabain is a selective Na+, K+-ATPase inhibitor, binds to α2 subunit and α3 subunit with Ki of 41 nM and 15 nM, respectively. |
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S1256
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Rufinamide (Banzel) |
Rufinamide, a triazole derivative, is an anticonvulsant medication. |
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