Gemcitabine(Gemzar)

Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites.

Catalog No.S1714
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Gemcitabine(Gemzar) Chemical Structure

Gemcitabine(Gemzar) Chemical Structure
Molecular Weight: 263.2

Validation & Quality Control

Customer Reviews(1)

Quality Control & MSDS

Related Compound Libraries

Gemcitabine(Gemzar) is available in the following compound libraries:

Product Information

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Product Description

Biological Activity

Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites. It is used alone or in combination with other medicines to treat cancer of the breast, ovary, pancreas, and lung. Gemcitabine interferes with the growth of cancer cells, which are eventually destroyed. [1, 2]

Chemical Information

Download Gemcitabine(Gemzar) SDF
Molecular Weight (MW) 263.2
Formula

C9H11F2N3O4

CAS No. 95058-81-4
Synonyms Gemzar
Solubility (25°C)
  • DMSO 15 mg/mL
  • Water <1 mg/mL
  • Ethanol <1 mg/mL
Storage 2 years -20°CPowder
2 weeks4°Cin DMSO
6 months-80°Cin DMSO
Chemical Name

Research Area

Customer Reviews (1)


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Rating
Source Dr. Helen Sadik of Johns Hopkins University. Gemcitabine (Gemzar) purchased from Selleck
Method MTT assays
Cell Lines MCF7 cells, MCF10A cells
Concentrations 0.01-100 μM
Incubation Time 48 h
Results Gemcitabine potently inhibited the survival of MCF10A cells in a dose-dependent manner. The highest level of inhibition was observed with Gemcitabine HCl in concentration of 0.01 μM in MCF7 cells

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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