Research Area
Product Type
United States ( Change Country )
Cisplatin Chemical Structure
Nelarabine (Arranon)
Nelarabine(Arranon) performes growth inhibitory activity (IC50= 1.61 μM) against MOLT-4 cells
Bleomycin sulfate
A glycopeptide antibiotic produced by the bacterium Streptomyces verticillus.
Carboplatin
This drug performed growth inhibitory activity in IGROV1 and OAW42 cells(IC50 of 25 and 30 mg/l,respectively).
Clafen (Cyclophosphamide)
This agent inhibited cell proliferation of NCI-H727 with IC50 at 9.3 nM.
Clofarabine
Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase
Oxaliplatin (Eloxatin)
Oxaliplatin (Eloxatin) is a 1,2-diaminocyclohexane (DACH) carrier ligand-based groups of platinum antitumor agent with IC50 of median 1.3, 6.2 and 1.5 mM for SW480 DLD1, HT29, respectively.
CCT239065
CCT239065 is a novel, selective, and efficacious nanomolar pyridopyrazinone V600E BRAF and LCK inhibitor with IC50 of 13 nM and 6 nM, respectively.
NSC-207895 (XI-006)
NSC-207895 (XI-006) is a derivative of nitrobenzofuroxan and an anticancer agent with an EC50 of 1 μM.
CX-5461
CX-5461 is a potent small-molecule rRNA synthesis inhibitor with an IC50 of 0.11 μM.
ABT-888 (Veliparib)
ABT-888 (Veliparib) is a potent poly (ADP-ribose) polymerase (PARP) inhibitor of PARP-1 and PARP-2 with Ki of 5.2 nM and 2.9 nM, respectively.
Biological Activity
Cisplatin is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, small cell lung cancer, ovarian cancer, lymphomas, and germ cell tumors. It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis . [1]
Product Information
| Molecular Weight (WM): | 300.05 |
|---|---|
| Formula: | Cl2H6N2Pt |
| CAS No.: | 15663-27-1 |
| Synonyms: |
cisplatinum, CDDP, Platinol and Platinol-AQ
|
| Dissolve in (25°C): | DMSO ≥60mg/mL |
| Water ≥1mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
Research Area
Notes:
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