Amiloride HCl

Catalog No.S1811 1 Product Citations

Amiloride HCl, a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells.

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In DMSO USD 130 In stock
USD 97 In stock
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Amiloride HCl  Chemical Structure

Amiloride HCl Chemical Structure
Molecular Weight: 266.09

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Product Description

Biological Activity

Amiloride hydrochloride(Midamor), a pyrazine compound inhibit sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. [1]

Chemical Information

Download Amiloride HCl SDF
Molecular Weight (MW) 266.09


CAS No. 2016-88-8
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Solubility (25°C) * In vitro DMSO 53 mg/mL (199 mM)
Water 6 mg/mL (22 mM)
Ethanol 5 mg/mL (18 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name 1-(3,5-diamino-2-chloropyrazine-6-carbonyl)guanidine hydrochloride

Research Area

Product Citations (1)

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