Amiloride HCl (Midamor)

Amiloride hydrochloride(Midamor), a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells.

Catalog No.S1811
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Amiloride HCl (Midamor) Chemical Structure
Molecular Weight: 266.09

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Amiloride HCl (Midamor) is available in the following compound libraries:

Product Information

Product Description

Biological Activity

Amiloride hydrochloride(Midamor), a pyrazine compound inhibit sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss. [1]

Chemical Information

Download Amiloride HCl (Midamor) SDF
Molecular Weight (MW) 266.09
Formula

C6H8ClN7O.HCl

CAS No. 2016-88-8, 2609-46-3(free base)
Synonyms Midamor, Colectril, Amipramizide, Guanamprazine hydrochloride
Solubility (25°C)
  • DMSO 53 mg/mL
  • Water 6 mg/mL
  • Ethanol 5 mg/mL
Storage 2 years -20°CPowder
2 weeks4°Cin DMSO
6 months-80°Cin DMSO
Chemical Name 1-(3,5-diamino-2-chloropyrazine-6-carbonyl)guanidine hydrochloride

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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