Product Categories

Smoothened Inhibitors & Chemicals

Smoothened Inhibitors & Chemicals (3)

water-soluble

Cat.No. Product Name Information Product Citations Customer Reviews
S2151 LDE225 (NVP-LDE225, Erismodegib) LDE225 (NVP-LDE225) is a smoothened antagonist with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
S2777 PF-5274857 PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively.
S2157 LY2940680 LY2940680 binds to the Smo receptor and potently inhibits Hh signaling.
Tags: smoothened antagonist | smoothened inhibitor | Smo inhibitor | smoothened agonist | Smo agonist | Smo antagonist | smoothened inhibitors | Smo antagonists | smoothened antagonist