|
S1200
|
Decitabine |
Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively. |
|
|
|
S2821
|
RG108 |
RG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM. |
|
|
|
S8006
|
BIX01294 |
BIX01294 is an inhitor of G9a histone methyltransferase with IC50 of 2.7 μM. |
|
|
|
S3147
|
Entacapone |
Entacapone inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. |
|
|
|
S7062
|
EPZ-5676 |
EPZ-5676 is an S-adenosyl methionine (SAM) competitive inhibitor of DOT11L with Ki of 80 pM. |
|
|
|
S7079
|
SGC 0946 |
SGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM. |
|
|
|
S7013
|
SGI-110 |
SGI-110 is a second generation DNA-hypomethyating agent. |
|
|
