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Decitabine Chemical Structure
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Biological Activity
Decitabine is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines. [1] Decitabine was demonstrated to have a wide range of anti-metabolic activities when tested against cultured cancer cells and to be an effective chemotherapeutic agent for acute myelogenous leukemia. However, because of 5-azacytidine
Chemical Information
| Molecular Weight (WM): | 228.21 |
|---|---|
| Formula: | C8H12N4O4 |
| CAS No.: | 2353-33-5 |
| Synonyms: |
Dacogen
|
| Dissolve in (25°C): | DMSO ≥46mg/mL |
| Water ≥10mg/mL | |
| Ethanol ≥2mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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Notes:
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