Procainamide HCl

Catalog No.S4294

Procainamide HCl Chemical Structure

Molecular Weight(MW): 271.79

Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.

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Biological Activity

Description Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.
Targets
DNA methyltransferase [1] Sodium channel [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 54 mg/mL (198.68 mM)
Water 54 mg/mL (198.68 mM)
Ethanol 54 mg/mL warmed (198.68 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 271.79
Formula

C13H22ClN3O

CAS No. 614-39-1
Storage powder
Synonyms N/A

Bio Calculators

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02575534 Not yet recruiting Arrhythmias University of Pittsburgh|UPMC October 2015 --
NCT01205529 Unknown status Atrial Fibrillation Vanderbilt University November 2010 --
NCT00702117 Completed Atrial Fibrillation|Tachycardia, Ventricular|Brugada Syndrome Hospital Clinic of Barcelona June 2008 Phase 4
NCT00383799 Terminated Ventricular Tachycardia|Wide QRS Tachycardia Hospital General Universitario Gregorio Marañon September 2005 Phase 4
NCT00000556 Completed Arrhythmia|Atrial Fibrillation|Cardiovascular Diseases|Heart Diseases National Heart, Lung, and Blood Institute (NHLBI) March 1995 Phase 3
NCT00000464 Completed Arrhythmia|Cardiovascular Diseases|Heart Arrest|Heart Diseases|Myocardial Infarction|Ventricular Fibrillation University of Washington|National Heart, Lung, and Blood Institute (NHLBI) April 1987 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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Sodium Channel Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID