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Smoothened

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Smoothened Inhibitors & Chemicals (3)

water-soluble

Cat.No. Product Name Information Product Citations Customer Reviews
S2151 LDE225 (NVP-LDE225, Erismodegib) LDE225 (NVP-LDE225) is a smoothened antagonist with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
S2777 PF-5274857 PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively.
S2157 LY2940680 LY2940680 binds to the Smo receptor and potently inhibits Hh signaling.
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Tags: Smo activity | smoothened pathway | smoothened pathway | smoothened signaling | Smo cancer | Smo pathway | smoothened signaling pathway | smoothened inhibitor review